{"id":"W4417303633","doi":"10.1093/narcan/zcaf050","title":"What is in a name? Rethinking SMUG1 in genome maintenance","year":2025,"lang":"en","type":"review","venue":"NAR Cancer","topic":"DNA Repair Mechanisms","field":"Biochemistry, Genetics and Molecular Biology","cited_by":1,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"Norges Forskningsråd; Kungliga Tekniska Högskolan; European Commission; European Federation of Pharmaceutical Industries and Associations; Ontario Institute for Cancer Research; Diamond Light Source; Kreftforeningen","keywords":"DNA glycosylase; Genome; DNA; Base excision repair; RNA; DNA repair; Nucleic acid","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0004317579,0.0004856208,0.0007382759,0.001351443,0.0002307444,0.0008293845,0.0005646053,0.0008769434,0.002156913],"category_scores_gemma":[0.0006456723,0.0001813275,0.0002681551,0.001143087,0.0004280625,0.0016377,0.0004882195,0.001732269,0.001407016],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000482902,"about_ca_system_score_gemma":0.0006414353,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0007329335,"about_ca_topic_score_gemma":0.001267465,"domain_scores_codex":[0.999896,0.00002044934,0.00001490618,0.00001908775,0.00003811441,0.00001141647],"domain_scores_gemma":[0.9997779,0.00009592859,0.00002318693,0.000007753342,0.00006436062,0.00003085539],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.00008044883,0.00003491624,0.0001431937,0.01006887,0.00006107165,0.0002456171,0.00009126328,0.0002787524,0.003304316,0.007646102,0.06589096,0.9121545],"study_design_scores_gemma":[0.000006390273,0.0000439574,0.0002880701,0.001353309,0.0000297326,0.0006356746,0.00003220547,0.00004884251,0.0003668868,0.001557916,0.9956284,0.000008599151],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.000138969,0.9971545,0.0001475907,0.0009093105,0.0006624453,0.00000200166,0.00001294927,0.000008307175,0.0009638799],"genre_scores_gemma":[0.0009241381,0.9967919,0.0001818551,0.0005871175,0.0005370305,0.000003004813,0.00002311944,0.000003328315,0.0009485225],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.002156913,"threshold_uncertainty_score":0.007215619,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02291456753407525,"score_gpt":0.3259449308147969,"score_spread":0.3030303632807216,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}