{"id":"W4417308142","doi":"10.7759/cureus.99214","title":"Effectiveness of Rituximab, Belimumab, and Thrombopoietin Receptor Agonists in Refractory Immune Thrombocytopenia Associated With Systemic Lupus Erythematosus: A Systematic Review and Meta-Analysis","year":2025,"lang":"en","type":"review","venue":"Cureus","topic":"Platelet Disorders and Treatments","field":"Medicine","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"","keywords":"Belimumab; Rituximab; Refractory (planetary science); Immune thrombocytopenia; Eltrombopag; Romiplostim; Thrombopoietin receptor; Thrombopoietin; Retrospective cohort study","routes":{"ca_aff":false,"ca_fund":false,"ca_venue":false,"about_ca":true,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.01249631,0.002808378,0.02067095,0.008101447,0.0006207597,0.003483816,0.002397275,0.002119987,0.002743843],"category_scores_gemma":[0.02547214,0.00158792,0.04019723,0.008685879,0.0006699688,0.001682008,0.001573588,0.001600781,0.0002838325],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.003066068,"about_ca_system_score_gemma":0.003661486,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.007959144,"about_ca_topic_score_gemma":0.01596101,"domain_scores_codex":[0.9912664,0.003900714,0.002819123,0.0008539355,0.0008932195,0.0002664952],"domain_scores_gemma":[0.9841433,0.01107664,0.002790103,0.0004410884,0.001295663,0.0002532991],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"meta_analysis","study_design_gemma":"meta_analysis","study_design_scores_codex":[0.001351976,0.00002778946,0.002722043,0.369855,0.6162529,0.0001147069,0.00007918519,0.0005951062,0.0001939628,0.0001136247,0.0004457783,0.008247891],"study_design_scores_gemma":[0.0003658127,0.0001197799,0.002164863,0.01969054,0.9762477,0.00006998618,0.0000339236,0.0001727346,0.00007500155,0.0001232455,0.0009172041,0.0000192614],"study_design_candidate":"meta_analysis","study_design_consensus":"meta_analysis","genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.005253176,0.992959,0.0004307418,0.0001707293,0.0001053575,0.0002787189,0.0005634971,0.00002081152,0.0002179136],"genre_scores_gemma":[0.1684024,0.8256487,0.002218846,0.000868022,0.0002177089,0.001228565,0.001091277,0.00002949898,0.0002949917],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.02067095,"threshold_uncertainty_score":0.0660876,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03033153446228005,"score_gpt":0.3223310343445754,"score_spread":0.2919994998822953,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}