{"id":"W4417329605","doi":"10.51731/cjht.2025.1306","title":"Inavolisib (Itovebi)","year":2025,"lang":"","type":"article","venue":"Canadian Journal of Health Technologies","topic":"Advanced Breast Cancer Therapies","field":"Medicine","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"","keywords":"Breast cancer; Metastatic breast cancer; Regimen; Reimbursement; Cancer; Fulvestrant; Palbociclib","routes":{"ca_aff":false,"ca_fund":false,"ca_venue":false,"about_ca":true,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0006908044,0.0007325914,0.001068875,0.0010399,0.0005894203,0.002242561,0.001664557,0.001908501,0.0734042],"category_scores_gemma":[0.001391078,0.0003157164,0.001064742,0.0006837269,0.0003864895,0.000979187,0.001012399,0.003719057,0.02917943],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.002479758,"about_ca_system_score_gemma":0.002990589,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.009921484,"about_ca_topic_score_gemma":0.02071862,"domain_scores_codex":[0.9995284,0.00006560757,0.00002608708,0.00007030118,0.0001876648,0.000121888],"domain_scores_gemma":[0.9996502,0.00003623881,0.00004495989,0.00002174311,0.0001075733,0.0001392506],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.004134023,0.0009711948,0.001314644,0.00155574,0.0001685009,0.0003687847,0.00007293853,0.0007064622,0.005800599,0.005211456,0.4423144,0.5373814],"study_design_scores_gemma":[0.006880735,0.001406268,0.00250747,0.0007924932,0.0001882859,0.001207377,0.00005880226,0.0009154325,0.002777836,0.002222128,0.9810127,0.00003047065],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"other","genre_gemma":"other","genre_scores_codex":[0.04705473,0.1832071,0.00632426,0.02527657,0.006606243,0.00322875,0.03278137,0.007567936,0.6879529],"genre_scores_gemma":[0.2739651,0.1112469,0.009572567,0.03817306,0.001721386,0.002440417,0.07966154,0.001176265,0.4820427],"genre_candidate":"other","genre_consensus":"other","teacher_disagreement_score":0.0734042,"threshold_uncertainty_score":0.2455615,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01762512935061559,"score_gpt":0.3259197549193014,"score_spread":0.3082946255686858,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}