{"id":"W4417329605","doi":"10.51731/cjht.2025.1306","title":"Inavolisib (Itovebi)","year":2025,"lang":"","type":"article","venue":"Canadian Journal of Health Technologies","topic":"Advanced Breast Cancer Therapies","field":"Medicine","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"","keywords":"Breast cancer; Metastatic breast cancer; Regimen; Reimbursement; Cancer; Fulvestrant; Palbociclib","routes":{"ca_aff":false,"ca_fund":false,"ca_venue":false,"about_ca":true,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.001285386,0.0004223195,0.001416874,0.003025032,0.0006188756,0.0000753345,0.0009845877,0.0005255117,0.0001484506],"category_scores_gemma":[0.002015026,0.0003866177,0.0002603664,0.001776225,0.001244984,0.000285514,0.00007185559,0.001991661,0.00002455511],"about_ca_system_candidate":true,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.003603932,"about_ca_system_score_gemma":0.03245008,"about_ca_topic_candidate":true,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.007490919,"about_ca_topic_score_gemma":0.004841347,"domain_scores_codex":[0.9959003,0.0001398354,0.001844096,0.0003429736,0.0003238274,0.001449017],"domain_scores_gemma":[0.9966767,0.0001776226,0.001285412,0.0007967202,0.0007629798,0.0003005372],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0001179815,0.00003452272,0.006299204,0.0006766989,0.0002812038,0.0003578856,0.000623445,0.00002816219,0.00004999943,0.006166577,0.005790116,0.9795742],"study_design_scores_gemma":[0.002308861,0.001015046,0.01609121,0.006834184,0.000117212,0.0006424751,0.01438499,0.00001328839,0.001140901,0.0253678,0.9318008,0.0002831865],"study_design_candidate":"design_other","study_design_consensus":null,"genre_codex":"review","genre_gemma":"empirical","genre_scores_codex":[0.01626152,0.776894,0.0037541,0.1964963,0.004618406,0.0005828826,0.00004931784,0.0001340857,0.001209446],"genre_scores_gemma":[0.9867579,0.006568175,0.001513814,0.004066436,0.00007547603,0.000008833424,0.000001754676,0.000039606,0.0009680182],"genre_candidate":"empirical","genre_consensus":null,"teacher_disagreement_score":0.979291,"threshold_uncertainty_score":0.9998586,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01762512935061559,"score_gpt":0.3259197549193014,"score_spread":0.3082946255686858,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}