{"id":"W4417416492","doi":"10.3389/fpls.2025.1712571","title":"The CRY1-HsF predicted interaction interface serves as a molecular platform for bioengineering or selecting modulating mutants","year":2025,"lang":"en","type":"article","venue":"Frontiers in Plant Science","topic":"Heat shock proteins research","field":"Biochemistry, Genetics and Molecular Biology","cited_by":1,"is_retracted":false,"has_abstract":true,"ca_institutions":"Université du Québec à Montréal; PROTEO; Université de Sherbrooke","funders":"Natural Sciences and Engineering Research Council of Canada","keywords":"Mutant; Identification (biology); Selection (genetic algorithm); Interface (matter); Process (computing); Stress (linguistics)","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001820678,0.0005094602,0.0003298013,0.0002431436,0.0002611814,0.0002326516,0.0003333859,0.0003295009,0.003145654],"category_scores_gemma":[0.000245192,0.000146694,0.0004584385,0.0002461211,0.0001159827,0.0002834242,0.0002455513,0.0005087718,0.001245197],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003802541,"about_ca_system_score_gemma":0.0003519013,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0007238866,"about_ca_topic_score_gemma":0.0007541616,"domain_scores_codex":[0.9998915,0.00001321065,0.000008421434,0.000030373,0.00003809156,0.00001822501],"domain_scores_gemma":[0.99988,0.00002434532,0.0000343076,0.00001592674,0.00001972804,0.00002560826],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001962591,0.00004058618,0.001524704,0.00008784197,0.00001533132,0.0002116656,0.00002254794,0.0005177757,0.9925612,0.0003374512,0.0002392728,0.004245262],"study_design_scores_gemma":[0.00004416712,0.0001832876,0.01316941,0.00002710995,0.00006646864,0.0007362303,0.0000473243,0.01417814,0.9607289,0.0003141318,0.01048345,0.00002139366],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.939238,0.001003457,0.05207261,0.0002092676,0.00007107069,0.0001134868,0.003428054,0.001509065,0.002354935],"genre_scores_gemma":[0.9604893,0.0003245459,0.03163921,0.00008980585,0.000009959081,0.00007083445,0.005625181,0.0001909836,0.001560294],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.003145654,"threshold_uncertainty_score":0.01052332,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01281839645367165,"score_gpt":0.3099248204133687,"score_spread":0.2971064239596971,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}