{"id":"W4417432454","doi":"10.1111/jdi.70193","title":"Evaluation of the effectiveness and safety of <scp>ONO</scp> ‐2910 for the treatment of diabetic polyneuropathy: An early Phase <scp>IIa</scp> , multicenter, randomized, placebo‐controlled, double‐blind study in Japanese patients","year":2025,"lang":"en","type":"article","venue":"Journal of Diabetes Investigation","topic":"Pain Mechanisms and Treatments","field":"Medicine","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"Ono Pharmaceutical","keywords":"Diabetes mellitus; Phase (matter); MEDLINE; Clinical trial; Primary care","routes":{"ca_aff":false,"ca_fund":false,"ca_venue":false,"about_ca":true,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001944379,0.001220936,0.002401667,0.0003065185,0.000450107,0.0006883584,0.0007153916,0.00126939,0.00262952],"category_scores_gemma":[0.001208416,0.0005069379,0.001570938,0.0003052203,0.0008994953,0.0005260539,0.0002725789,0.001651414,0.0003201502],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0006716429,"about_ca_system_score_gemma":0.001546143,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001451331,"about_ca_topic_score_gemma":0.00300904,"domain_scores_codex":[0.9993625,0.0003691019,0.0000523132,0.00008000535,0.00006602056,0.00007010053],"domain_scores_gemma":[0.9987898,0.0002798003,0.0003632458,0.00006152249,0.0001030808,0.0004024934],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"randomized_trial","study_design_scores_codex":[0.9308343,0.01967425,0.002483608,0.001896065,0.001500678,0.00009329047,0.0001185954,0.0003291479,0.0092871,0.0000708102,0.0005504314,0.03316175],"study_design_scores_gemma":[0.7765921,0.2138556,0.007013188,0.00007604848,0.0007707263,0.00006362923,0.00003713117,0.000338473,0.0008581092,0.00003506809,0.000344042,0.00001593493],"study_design_candidate":"randomized_trial","study_design_consensus":"randomized_trial","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9947578,0.002986853,0.0001557346,0.0001271395,0.00007874263,0.001117868,0.0001623808,0.00001459358,0.0005987382],"genre_scores_gemma":[0.9935162,0.002767704,0.0008533479,0.0004670728,0.0002266903,0.001139743,0.0004269078,0.000007642382,0.0005947269],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.00262952,"threshold_uncertainty_score":0.01028299,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02639989492426337,"score_gpt":0.3176863908176369,"score_spread":0.2912864958933736,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}