{"id":"W4417434980","doi":"10.3390/v17121638","title":"AI-Powered Identification of Human Cell Surface Protein Interactors of the Hemagglutinin Glycoprotein of High-Pandemic-Risk H5N1 Influenza Virus","year":2025,"lang":"en","type":"article","venue":"Viruses","topic":"Influenza Virus Research Studies","field":"Medicine","cited_by":1,"is_retracted":false,"has_abstract":true,"ca_institutions":"Montreal Clinical Research Institute","funders":"Alliance de recherche numérique du Canada; Institut de Recherche Clinique De Montréal","keywords":"Influenza A virus subtype H5N1; Hemagglutinin (influenza); Glycoprotein; Influenza A virus; Virus; Host (biology); Tropism; Glycan; Identification (biology); Tissue tropism","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000489268,0.0005746961,0.0004910177,0.0005604687,0.0002517783,0.000581529,0.0003240053,0.0004181166,0.0008113122],"category_scores_gemma":[0.0006510299,0.0001260177,0.0006842819,0.0003783498,0.0001396502,0.0002791824,0.0003209154,0.0003608569,0.0003956002],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004155108,"about_ca_system_score_gemma":0.000484395,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00203772,"about_ca_topic_score_gemma":0.002021035,"domain_scores_codex":[0.9998259,0.00003946041,0.000008989716,0.00004649683,0.00005385071,0.00002535757],"domain_scores_gemma":[0.9998822,0.00004903739,0.00001851385,0.00001104097,0.00002390115,0.00001524809],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"simulation_or_modeling","study_design_scores_codex":[0.0009573844,0.0007286237,0.04067839,0.0003726642,0.0002845313,0.0006958155,0.0001679181,0.08217145,0.7422429,0.002214881,0.003100171,0.1263852],"study_design_scores_gemma":[0.00002708968,0.0002508964,0.01014255,0.00001006945,0.000071911,0.0002314821,0.00006390976,0.8604291,0.1244153,0.0009286178,0.003412659,0.00001652791],"study_design_candidate":"simulation_or_modeling","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.8975977,0.001005078,0.09380311,0.0002993196,0.00002979544,0.000218831,0.002052579,0.001928279,0.003065419],"genre_scores_gemma":[0.8988693,0.0005670884,0.09299664,0.0001649793,0.00001305762,0.00009934035,0.006149168,0.00007474535,0.001065657],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.00203772,"threshold_uncertainty_score":0.004051685,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.04836508324601069,"score_gpt":0.3810146766842167,"score_spread":0.332649593438206,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}