{"id":"W4417478436","doi":"10.5376/mp.2025.16.0029","title":"Restoration of Cotton Disease Resistance by CRISPR-Mediated Disruption of Key Genes in Drug-Resistant Pathogens","year":2025,"lang":"","type":"article","venue":"Molecular Pathogens","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":false,"ca_institutions":"","funders":"","keywords":"Gene; Key (lock); Disease; Plant disease resistance; Resistance (ecology); Genome; DNA Transposable Elements","routes":{"ca_aff":false,"ca_fund":false,"ca_venue":true,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0004901909,0.0005040469,0.0006211891,0.0003198199,0.00007598412,0.00002569654,0.0003667579,0.0003499075,0.0000132959],"category_scores_gemma":[0.0004082591,0.000602224,0.0003391773,0.0007988354,0.0002247377,0.00001028326,0.0001912597,0.0001919041,0.000002315929],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00009561711,"about_ca_system_score_gemma":0.0003814715,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00006219187,"about_ca_topic_score_gemma":0.00044466,"domain_scores_codex":[0.9965304,0.0003601977,0.001239956,0.0008916176,0.0004306553,0.0005471566],"domain_scores_gemma":[0.9979157,0.00004610532,0.0003951533,0.001073068,0.0003570815,0.0002128504],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0007782214,0.0004053804,0.003407312,0.0009450122,0.0001257688,0.00006831223,0.0002107989,0.002293366,0.989749,0.0003038092,0.000709342,0.001003698],"study_design_scores_gemma":[0.001445777,0.000157245,0.00941079,0.0005475339,0.0002790159,0.000001008816,0.0002915753,0.0008905165,0.9711496,0.0001097934,0.01513775,0.0005793656],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.8812679,0.0700569,0.04511362,0.000274951,0.0003370367,0.000745563,0.001719245,0.00001444543,0.0004703152],"genre_scores_gemma":[0.9928073,0.004324334,0.0009373571,0.00007617108,0.00003941951,0.00006522115,0.001125187,0.00006177017,0.0005632493],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.1115394,"threshold_uncertainty_score":0.9996429,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.003575015947493673,"score_gpt":0.2611427737027478,"score_spread":0.2575677577552541,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}