{"id":"W4417521668","doi":"10.1093/cid/ciaf651","title":"Evaluating the Impact of Implementing and Scaling-Up the Use of Syphilis Rapid/Point-of-Care Tests: An Interrupted Time Series Analysis of New Syphilis Positivity Rates in Alberta, Canada","year":2025,"lang":"en","type":"article","venue":"Clinical Infectious Diseases","topic":"Syphilis Diagnosis and Treatment","field":"Medicine","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"Institute of Population and Public Health; Provincial Laboratory of Public Health; University of Calgary; Alberta Hospital Edmonton; University of Alberta; Alberta Health Services","funders":"Canadian Institutes of Health Research; Indigenous Services Canada; Alberta Health; Alberta Precision Laboratories; Alberta Health Services","keywords":"Syphilis; Interrupted Time Series Analysis; Interrupted time series; Congenital syphilis; Early syphilis; Treponematosis","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":true,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.005866284,0.0005407156,0.0004044934,0.001373374,0.0007023629,0.001332352,0.0018676,0.0004481844,0.001042271],"category_scores_gemma":[0.0103678,0.0002755073,0.0008522723,0.002602278,0.0007350718,0.0003526907,0.0008052833,0.0009374262,0.00009585493],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.02889077,"about_ca_system_score_gemma":0.0312776,"about_ca_topic_candidate":true,"about_ca_topic_consensus":true,"about_ca_topic_score_codex":0.9847202,"about_ca_topic_score_gemma":0.9718415,"domain_scores_codex":[0.9963616,0.0008092806,0.0001821764,0.0003554778,0.001542535,0.0007489137],"domain_scores_gemma":[0.9913408,0.001859214,0.002139294,0.000348651,0.003331925,0.0009802504],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.0005350224,0.0001835695,0.9781221,0.00007794788,0.0003744421,0.0001117127,0.000602654,0.008136668,0.0002246671,0.000439564,0.001110732,0.01008075],"study_design_scores_gemma":[0.00003905875,0.0002078901,0.9763122,0.00004382068,0.0001729601,0.00002793208,0.0008979123,0.02098733,0.0001755809,0.00008939307,0.001024436,0.00002160649],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9931471,0.0007277273,0.001262518,0.0004292465,0.00002394911,0.00009105913,0.002851101,0.00003046093,0.001436767],"genre_scores_gemma":[0.9947289,0.0003188938,0.001210439,0.0001055929,0.00001054913,0.00003855909,0.002691867,0.000008312692,0.0008870153],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.02889077,"threshold_uncertainty_score":0.2096182,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.08195817963224554,"score_gpt":0.4531734150885819,"score_spread":0.3712152354563364,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}