{"id":"W4417523935","doi":"10.1021/acs.analchem.5c05530","title":"Coupling Liquid Chromatography to Orbitrap Isotope Ratio Mass Spectrometry: Overcoming Isotope Effects of Chromatography and Amount-Dependency by Peak Homogenization","year":2025,"lang":"en","type":"article","venue":"Analytical Chemistry","topic":"Isotope Analysis in Ecology","field":"Environmental Science","cited_by":2,"is_retracted":false,"has_abstract":true,"ca_institutions":"Thermo Fisher Scientific (Canada)","funders":"International Atomic Energy Agency","keywords":"Analyte; Isotopologue; Mass spectrometry; Analytical Chemistry (journal); Orbitrap; Isotope; Stable isotope ratio","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.003086486,0.001531119,0.0009959836,0.001207979,0.0005996133,0.001251448,0.001430819,0.001530326,0.001551518],"category_scores_gemma":[0.004739388,0.0009217287,0.0007568081,0.001065283,0.001444241,0.001282712,0.001704656,0.001849818,0.001467936],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0008772928,"about_ca_system_score_gemma":0.001589922,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001175367,"about_ca_topic_score_gemma":0.002063442,"domain_scores_codex":[0.9953418,0.000616043,0.0002209361,0.001139637,0.002402778,0.0002788966],"domain_scores_gemma":[0.9976761,0.0008274365,0.000421854,0.0003282156,0.0006604358,0.00008600487],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001102771,0.00003670695,0.0004368507,0.0001148188,0.0000388541,0.00006745225,0.00005091679,0.0001479019,0.9869246,0.0002060306,0.0001848704,0.01168071],"study_design_scores_gemma":[0.00001594034,0.0001617035,0.00203349,0.00001276652,0.00003651028,0.0003728349,0.00002289606,0.005095266,0.9889832,0.0002724921,0.00296022,0.00003269473],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"methods","genre_gemma":"methods","genre_scores_codex":[0.2647399,0.005891624,0.7191069,0.0005976673,0.0004541445,0.000674241,0.0004131876,0.005152442,0.002969915],"genre_scores_gemma":[0.3473971,0.004922638,0.6348138,0.001821949,0.0002554217,0.001225009,0.00128395,0.002240435,0.006039806],"genre_candidate":"methods","genre_consensus":"methods","teacher_disagreement_score":0.003086486,"threshold_uncertainty_score":0.01632315,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.002998332098445335,"score_gpt":0.2199393490240505,"score_spread":0.2169410169256052,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}