{"id":"W4417526934","doi":"10.1016/j.cmi.2025.12.014","title":"Efficacy, safety, pharmacokinetics, immunogenicity, and serum neutralizing activity of AZD7442 (tixagevimab-cilgavimab) in patients hospitalized with COVID-19: long-term results from the DisCoVeRy trial","year":2025,"lang":"en","type":"article","venue":"Clinical Microbiology and Infection","topic":"SARS-CoV-2 and COVID-19 Research","field":"Medicine","cited_by":1,"is_retracted":false,"has_abstract":false,"ca_institutions":"Hotel Dieu Hospital","funders":"Belgian Health Care Knowledge Centre; Fonds Erasme; Sanofi","keywords":"Clinical trial; MEDLINE; Antibody; Immunopathology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.002353991,0.00139647,0.002228309,0.0003949034,0.0004774537,0.001460099,0.0007780504,0.001717303,0.00130981],"category_scores_gemma":[0.002044819,0.0005471308,0.001800901,0.0004816747,0.001133746,0.00181405,0.0003709812,0.002963708,0.0004697118],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.001073693,"about_ca_system_score_gemma":0.0007875511,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0007831741,"about_ca_topic_score_gemma":0.0006860128,"domain_scores_codex":[0.9989827,0.0004278287,0.00006497318,0.000174288,0.0001241947,0.0002259568],"domain_scores_gemma":[0.998531,0.0003698782,0.0004209375,0.0001470263,0.00009891683,0.0004323053],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"randomized_trial","study_design_scores_codex":[0.8431618,0.0201774,0.03807992,0.0003024896,0.003116739,0.0002775168,0.0002755955,0.001536655,0.01976799,0.0001621858,0.001784227,0.07135746],"study_design_scores_gemma":[0.3206539,0.5175095,0.1454669,0.00007562202,0.00314529,0.0006451553,0.0002151777,0.002359679,0.007195598,0.0003629133,0.002217852,0.0001523331],"study_design_candidate":"randomized_trial","study_design_consensus":"randomized_trial","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9973947,0.001598164,0.0001039566,0.0001318956,0.00003112568,0.00008801607,0.0002959865,0.00001704786,0.0003390467],"genre_scores_gemma":[0.9971229,0.00070693,0.0001756275,0.0003241916,0.0001563075,0.0001264155,0.0009266319,0.000007332753,0.0004535591],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002353991,"threshold_uncertainty_score":0.01244926,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.04053992931395622,"score_gpt":0.3928989102966635,"score_spread":0.3523589809827073,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}