{"id":"W4417530910","doi":"10.1016/j.esmorc.2025.100062","title":"MINNELIDE IS A NOVEL THERAPEUTIC INHIBITOR OF CIC::DUX4 SARCOMA","year":2025,"lang":"en","type":"article","venue":"ESMO rare cancers.","topic":"Magnesium in Health and Disease","field":"Nursing","cited_by":0,"is_retracted":false,"has_abstract":false,"ca_institutions":"Princess Margaret Cancer Centre","funders":"","keywords":"Sarcoma; Cancer; Immunotherapy; Soft tissue sarcoma; Drug","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001088442,0.0001773087,0.0002681406,0.000151575,0.0001183134,0.00002016499,0.0002156668,0.0001141018,0.0007608674],"category_scores_gemma":[0.0000880916,0.0001738109,0.0001189411,0.000427233,0.0001040154,0.00008682597,0.00003895611,0.0001564655,0.00002101538],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002685687,"about_ca_system_score_gemma":0.0004570515,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001348244,"about_ca_topic_score_gemma":0.000114497,"domain_scores_codex":[0.9986771,0.00004324324,0.0003636807,0.000322175,0.0002134361,0.0003803723],"domain_scores_gemma":[0.9990337,0.0001252573,0.0001204006,0.0004302822,0.000126693,0.0001636112],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"not_applicable","study_design_gemma":"not_applicable","study_design_scores_codex":[0.009123942,0.001096464,0.1402747,0.01256928,0.0001995328,0.00004403628,0.007276993,0.0001231411,0.02451724,0.006813947,0.4074579,0.3905028],"study_design_scores_gemma":[0.01169356,0.0009435553,0.1563114,0.001022499,0.0006648031,0.00001213028,0.00206059,0.002691833,0.2125865,0.007825093,0.6028058,0.001382271],"study_design_candidate":"not_applicable","study_design_consensus":"not_applicable","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.8695884,0.02598305,0.00083934,0.04196671,0.01109219,0.001851376,0.0005533783,0.0003748044,0.04775078],"genre_scores_gemma":[0.9826685,0.00001299454,0.0002599631,0.01567578,0.0002576568,0.0000567407,0.00001213976,0.00002038501,0.001035913],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.3891205,"threshold_uncertainty_score":0.8330964,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01910175830934603,"score_gpt":0.3049709616630899,"score_spread":0.2858692033537439,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}