{"id":"W4417535594","doi":"10.1002/2211-5463.70186","title":"<scp>HIV</scp> ‐1 establishes immediate latency in T cells expressing the viral Nef protein","year":2025,"lang":"en","type":"article","venue":"FEBS Open Bio","topic":"HIV Research and Treatment","field":"Immunology and Microbiology","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of British Columbia","funders":"Natural Sciences and Engineering Research Council of Canada; Canadian Institutes of Health Research; National Institutes of Health","keywords":"mCherry; Reporter gene; Green fluorescent protein; Latency (audio); Transcription (linguistics); HEK 293 cells; Capsid; Cell culture","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002175417,0.0002576046,0.0002112993,0.0001903489,0.0001900056,0.0003972123,0.0003307333,0.0003126239,0.001213102],"category_scores_gemma":[0.0001541211,0.0001450914,0.0001946986,0.0001637752,0.00028773,0.0002071482,0.0002092331,0.0008199844,0.0006500033],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004816837,"about_ca_system_score_gemma":0.000229031,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001068765,"about_ca_topic_score_gemma":0.001473617,"domain_scores_codex":[0.9998435,0.00002904586,0.0000139737,0.00002272273,0.00005552487,0.00003518977],"domain_scores_gemma":[0.9998658,0.00003339932,0.00003154967,0.000029635,0.00001119732,0.00002833601],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00002619317,0.00001544212,0.000105299,0.000009904112,0.000001965842,0.00003649607,0.00001283777,0.00004586477,0.9987949,0.0001655323,0.00005043484,0.0007350063],"study_design_scores_gemma":[0.00001403386,0.0001603247,0.002444851,0.000006075912,0.000007017295,0.0003469223,0.00001971938,0.001169745,0.9913086,0.00006708372,0.004450044,0.000005492878],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9880448,0.0004816913,0.007343855,0.00009493381,0.00002558415,0.000099175,0.0008163478,0.0001944619,0.002899168],"genre_scores_gemma":[0.9814817,0.0002991208,0.01148698,0.00006974922,0.00001168583,0.00007526801,0.001628894,0.0001038515,0.004842666],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001213102,"threshold_uncertainty_score":0.004058242,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01526328847951971,"score_gpt":0.2712346770741307,"score_spread":0.255971388594611,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}