{"id":"W4417535594","doi":"10.1002/2211-5463.70186","title":"<scp>HIV</scp> ‐1 establishes immediate latency in T cells expressing the viral Nef protein","year":2025,"lang":"en","type":"article","venue":"FEBS Open Bio","topic":"HIV Research and Treatment","field":"Immunology and Microbiology","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of British Columbia","funders":"Natural Sciences and Engineering Research Council of Canada; Canadian Institutes of Health Research; National Institutes of Health","keywords":"mCherry; Reporter gene; Green fluorescent protein; Latency (audio); Transcription (linguistics); HEK 293 cells; Capsid; Cell culture","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.0003998713,0.0001690345,0.0002350208,0.0001188663,0.0002937541,0.0002099941,0.0007978923,0.0001597928,0.0002041072],"category_scores_gemma":[0.000143901,0.0001073232,0.00005691052,0.0002687435,0.0001968275,0.000238273,0.000579786,0.0003640337,0.002309502],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00005613155,"about_ca_system_score_gemma":0.0002012514,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001281136,"about_ca_topic_score_gemma":0.0002475741,"domain_scores_codex":[0.9984923,0.0003404549,0.000240179,0.0003313233,0.00004174965,0.0005539698],"domain_scores_gemma":[0.9992616,0.0002205355,0.00005956224,0.0003959103,0.00003503183,0.00002733612],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.000218847,0.0008215058,0.02962327,0.00005866377,0.0003339954,0.0001127945,0.002006637,0.000009891884,0.7910138,0.001605004,0.1506019,0.02359374],"study_design_scores_gemma":[0.003121771,0.0001592036,0.02639015,0.0001964632,0.00002161676,0.00000351779,0.0008579459,0.000006060392,0.6135417,0.0008112589,0.3547956,0.00009473503],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.934859,0.003777657,0.00003293109,0.001438183,0.0003665084,0.00184875,0.0001065201,0.00003969151,0.05753081],"genre_scores_gemma":[0.9157542,0.0001061256,0.0001290292,0.0001832802,0.00002479535,0.0003836368,0.000176573,0.00001303593,0.08322936],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.2041937,"threshold_uncertainty_score":0.9984673,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01526328847951971,"score_gpt":0.2712346770741307,"score_spread":0.255971388594611,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}