{"id":"W448943630","doi":"10.1371/journal.pone.0125315","title":"Differential Effects of Tra2ß Isoforms on HIV-1 RNA Processing and Expression","year":2015,"lang":"en","type":"article","venue":"PLoS ONE","topic":"RNA Research and Splicing","field":"Biochemistry, Genetics and Molecular Biology","cited_by":15,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Toronto","funders":"National Institutes of Health; National Institute of Allergy and Infectious Diseases; Canadian Institutes of Health Research; Ontario HIV Treatment Network","keywords":"RNA; Gene isoform; Context (archaeology); RNA splicing; Biology; Gene expression; Small interfering RNA; Viral replication; Non-coding RNA; Cell biology; Virology; Virus; Genetics; Gene","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001946115,0.0004277301,0.0001884067,0.0002219124,0.0002004107,0.0004658099,0.000174534,0.0001900377,0.0009740536],"category_scores_gemma":[0.00009909573,0.0001111953,0.0002776919,0.0001603298,0.00017692,0.0002244194,0.0001515016,0.0004608819,0.0003338203],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002077452,"about_ca_system_score_gemma":0.0001751793,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0005501668,"about_ca_topic_score_gemma":0.001036535,"domain_scores_codex":[0.999871,0.00001965517,0.00001720559,0.00002963914,0.00002983866,0.00003268558],"domain_scores_gemma":[0.9998657,0.0000199056,0.000034709,0.00002077853,0.00002055285,0.00003843459],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00006258716,0.000006006972,0.0001098773,0.00001210043,0.000003139788,0.0000189022,0.000005513328,0.00001911528,0.9993756,0.00003744668,0.000006827857,0.0003429198],"study_design_scores_gemma":[0.000008958636,0.00015214,0.005001449,0.000006114249,0.00002519768,0.0003662465,0.00003700758,0.0004273648,0.9916598,0.00004910542,0.002260181,0.000006488573],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9957511,0.001475435,0.001195173,0.00004536951,0.00001710167,0.00001189948,0.0003097825,0.00003019639,0.001163881],"genre_scores_gemma":[0.9917406,0.001460101,0.002565942,0.00005994662,0.00001544527,0.00002918677,0.0008827564,0.0000342552,0.003211705],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0009740536,"threshold_uncertainty_score":0.003258526,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02565270622565846,"score_gpt":0.2500652793542191,"score_spread":0.2244125731285607,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}