{"id":"W45844253","doi":"10.1023/a:1020625423524","title":"Phase II Study of Marimastat (BB-2516) in Malignant Melanoma – A Clinical and Tumor Biopsy Study of the National Cancer Institute of Canada Clinical Trials Group","year":2002,"lang":"en","type":"article","venue":"Investigational New Drugs","topic":"Protease and Inhibitor Mechanisms","field":"Biochemistry, Genetics and Molecular Biology","cited_by":45,"is_retracted":false,"has_abstract":false,"ca_institutions":"Queen's University; Hôpital Notre-Dame; Hamilton Regional Laboratory Medicine Program; Princess Margaret Cancer Centre; Nova Scotia Cancer Centre; Ottawa Regional Cancer Foundation; Ontario Institute for Cancer Research","funders":"National Cancer Institute","keywords":"Medicine; Melanoma; Cancer; Biopsy; Internal medicine; Gastroenterology; Fibrosis; Clinical trial; Necrosis; Matrix metalloproteinase; Pathology; Oncology; Cancer research","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":true,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001783199,0.0001377133,0.0004511635,0.00004766245,0.00005943429,0.000004761438,0.0002086193,0.00008020414,0.00002980718],"category_scores_gemma":[0.001197703,0.0001032848,0.0000879656,0.0001618722,0.000223702,0.00001118547,0.0001796213,0.0001298851,1.375378e-7],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00002024516,"about_ca_system_score_gemma":0.001014613,"about_ca_topic_candidate":true,"about_ca_topic_consensus":true,"about_ca_topic_score_codex":0.03006134,"about_ca_topic_score_gemma":0.04928905,"domain_scores_codex":[0.9970191,0.0005734649,0.001452539,0.0003309072,0.000497325,0.0001266583],"domain_scores_gemma":[0.9987558,0.0001260492,0.0006307594,0.000190781,0.0001706788,0.0001259677],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00218733,0.0334558,0.4240381,0.0001412016,0.001523314,0.00004034627,0.003070739,0.0004890439,0.4928465,0.003633038,0.02974865,0.008825944],"study_design_scores_gemma":[0.16217,0.04439677,0.3112274,0.000915806,0.000924102,0.00007934892,0.005954042,0.003896183,0.4421536,0.012956,0.01331618,0.00201059],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9980778,0.0002005691,0.000007389086,0.0003570916,0.0003695903,0.0008061327,0.0001190291,0.000001697754,0.00006076102],"genre_scores_gemma":[0.9990056,0.0000188078,0.0002072659,0.0003182312,0.00026558,0.00004385834,0.00001731015,0.000008931674,0.0001144744],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.1599827,"threshold_uncertainty_score":0.9763976,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.1056938063737493,"score_gpt":0.3762751140693367,"score_spread":0.2705813076955874,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}