{"id":"W46269388","doi":"10.1593/neo.101524","title":"Optimization of Circulating Biomarkers of Obatoclax-Induced Cell Death in Patients with Small Cell Lung Cancer","year":2011,"lang":"en","type":"article","venue":"Neoplasia","topic":"Lung Cancer Research Studies","field":"Medicine","cited_by":21,"is_retracted":false,"has_abstract":true,"ca_institutions":"Xenon Pharmaceuticals (Canada)","funders":"Cancer Research UK; Moffitt Cancer Center","keywords":"Etoposide; Carboplatin; Lung cancer; Pharmacology; Medicine; Cisplatin; Oncology; Internal medicine; Apoptosis; Chemotherapy; Cancer research; Biology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0006213218,0.0005407909,0.001187381,0.0004292175,0.0002262829,0.0005670476,0.0002508118,0.0003781255,0.0005199359],"category_scores_gemma":[0.001499297,0.0001843114,0.0002251627,0.0003986189,0.0002158218,0.0003174598,0.0002013433,0.0006400433,0.0002023132],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003429494,"about_ca_system_score_gemma":0.000433461,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00037896,"about_ca_topic_score_gemma":0.0005228138,"domain_scores_codex":[0.9996275,0.0001575405,0.00003901403,0.00006564137,0.00006242224,0.00004792094],"domain_scores_gemma":[0.9993321,0.0001802201,0.0001957155,0.00003844656,0.00008571018,0.000167743],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.1192271,0.002917668,0.4896895,0.0004789371,0.0004395839,0.001006112,0.0005269108,0.0052372,0.1736167,0.000254613,0.002119043,0.2044868],"study_design_scores_gemma":[0.006669952,0.1048398,0.7614951,0.0001053597,0.0007042647,0.002374252,0.00032602,0.01168726,0.1037425,0.0004973244,0.007490698,0.00006764962],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9945478,0.002993245,0.000892468,0.00009757057,0.00002068245,0.0003110228,0.0002477501,0.0000679717,0.0008215808],"genre_scores_gemma":[0.9970464,0.0004390921,0.001189632,0.000145797,0.00003004705,0.0002632876,0.0005797365,0.000007909909,0.0002980072],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001187381,"threshold_uncertainty_score":0.003285885,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02953228557169934,"score_gpt":0.2772463582751328,"score_spread":0.2477140727034335,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}