{"id":"W46861897","doi":"10.1182/blood.v96.13.4185","title":"Human hematopoietic stem cells stimulated to proliferate in vitro lose engraftment potential during their S/G2/M transit and do not reenter G0","year":2000,"lang":"en","type":"article","venue":"Blood","topic":"Hematopoietic Stem Cell Transplantation","field":"Medicine","cited_by":234,"is_retracted":false,"has_abstract":true,"ca_institutions":"BC Cancer Agency","funders":"","keywords":"Stem cell; Haematopoiesis; Biology; Stem cell factor; Cell biology; Cord blood; CD34; Homing (biology); Interleukin 3; Population; Progenitor cell; Molecular biology; Immunology; Cancer research; T cell; IL-2 receptor; Medicine; Immune system","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00008491243,0.0003137881,0.0002329552,0.0002648742,0.0001285061,0.0002685809,0.0001200043,0.0001658429,0.002692116],"category_scores_gemma":[0.0001127089,0.0001048052,0.000134123,0.0002637747,0.0002079759,0.0001280905,0.0001613874,0.000241279,0.001045253],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002188614,"about_ca_system_score_gemma":0.0002014036,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001172223,"about_ca_topic_score_gemma":0.001565376,"domain_scores_codex":[0.999949,0.000007555337,0.00000481899,0.0000108172,0.00001616457,0.00001167041],"domain_scores_gemma":[0.9999223,0.00001769087,0.00001632098,0.00001890473,0.00001062231,0.00001422412],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.000236405,0.00002620534,0.001523549,0.00005363082,0.000008521684,0.00006351883,0.00006867904,0.0001469505,0.9912201,0.0002001132,0.0001425751,0.006309867],"study_design_scores_gemma":[0.00002437366,0.0006297371,0.02800527,0.00001785743,0.00002221992,0.0004544384,0.00007423945,0.0006084524,0.9601457,0.0001565059,0.009854945,0.000006182578],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9889147,0.003491047,0.003010902,0.00005631463,0.0000176135,0.0000502508,0.0006354518,0.0001847581,0.003639075],"genre_scores_gemma":[0.9888569,0.001387581,0.001886515,0.00008682839,0.00001052678,0.00006337016,0.002106156,0.00003029315,0.00557199],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002692116,"threshold_uncertainty_score":0.009005964,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01043591337437482,"score_gpt":0.2298768355543121,"score_spread":0.2194409221799373,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}