{"id":"W49499134","doi":"10.1007/978-1-60327-565-1_20","title":"Isolation of Monoclonal Antibody Fragments from Phage Display Libraries","year":2009,"lang":"en","type":"article","venue":"Methods in molecular biology","topic":"Monoclonal and Polyclonal Antibodies Research","field":"Medicine","cited_by":31,"is_retracted":false,"has_abstract":true,"ca_institutions":"Institute for Biological Sciences","funders":"","keywords":"Panning (audio); Phage display; Phagemid; Monoclonal antibody; Antibody; Biology; Recombinant DNA; Peptide library; Antigen; Molecular biology; Immunoglobulin light chain; Escherichia coli; Virology; Gene; Bacteriophage; Peptide sequence; Genetics","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0004330916,0.0001554887,0.00044522,0.000189934,0.00003014753,0.000007587312,0.0001539375,0.000186305,0.0002157789],"category_scores_gemma":[0.0002324849,0.0001241864,0.0001223985,0.0002470192,0.0001622445,0.00004541227,0.00007527343,0.0002657281,0.00000826737],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00001831218,"about_ca_system_score_gemma":0.00006051356,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0001999387,"about_ca_topic_score_gemma":0.000001971573,"domain_scores_codex":[0.9983352,0.0005429323,0.0003789672,0.0003106259,0.0001470308,0.0002852742],"domain_scores_gemma":[0.9992738,0.0002615827,0.0000863421,0.0002435501,0.00004782728,0.00008692567],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0004108989,0.000157205,0.06105441,0.00001456802,0.00005639527,0.0000681426,0.0000947487,0.000005554418,0.9069701,0.008102459,0.00002126479,0.02304428],"study_design_scores_gemma":[0.001372872,0.0009759312,0.230771,0.00008276539,0.00004296597,0.00001999594,0.00003168277,0.002672794,0.693514,0.06779413,0.002518497,0.000203305],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"methods","genre_scores_codex":[0.5102795,0.001620004,0.4850583,0.0008034666,0.00008580334,0.0001676269,0.00002827172,0.00001325599,0.001943775],"genre_scores_gemma":[0.2459736,0.0001229481,0.7527082,0.0006724013,0.00006586459,0.000005267639,0.0002720514,0.000009877239,0.0001698002],"genre_candidate":"methods","genre_consensus":null,"teacher_disagreement_score":0.2676499,"threshold_uncertainty_score":0.5064176,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03024098073710645,"score_gpt":0.4464166625707082,"score_spread":0.4161756818336017,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}