{"id":"W49633820","doi":"10.1023/a:1020083008017","title":"Candidate tumour suppressor LUCA-15 can regulate multiple apoptotic pathways","year":2002,"lang":"en","type":"article","venue":"APOPTOSIS","topic":"Cell death mechanisms and regulation","field":"Biochemistry, Genetics and Molecular Biology","cited_by":38,"is_retracted":false,"has_abstract":false,"ca_institutions":"Northeast Cancer Centre","funders":"Medical Research Council; Wellcome Trust","keywords":"Apoptosis; Jurkat cells; Fas receptor; Cell biology; Biology; Programmed cell death; Inhibitor of apoptosis domain; Molecular biology; Genetics; Caspase; T cell","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001829293,0.0004096206,0.0002924137,0.000381398,0.0002394808,0.0005465476,0.0002666266,0.000220052,0.00105383],"category_scores_gemma":[0.000197577,0.0001468266,0.0003032925,0.0001707314,0.0002424722,0.0002751915,0.0003767169,0.0004942604,0.0005371307],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0006403924,"about_ca_system_score_gemma":0.0002472527,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0005208133,"about_ca_topic_score_gemma":0.000752636,"domain_scores_codex":[0.999844,0.00001917497,0.00001117658,0.00003778259,0.00003978151,0.00004807836],"domain_scores_gemma":[0.9997957,0.00002971488,0.00006582017,0.00002562135,0.0000226344,0.00006048887],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001252684,0.00001529649,0.0006106799,0.00001814454,0.000006348083,0.00007675941,0.000005075973,0.0001087994,0.9972572,0.0002823653,0.00005374813,0.001440306],"study_design_scores_gemma":[0.00001103013,0.00008522804,0.004183204,0.000003101401,0.00001069472,0.0002423163,0.000008893619,0.0009874714,0.9923694,0.0001301433,0.001964323,0.000004201857],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9878953,0.003108295,0.005746929,0.000129049,0.00005901253,0.0000270717,0.0005176528,0.0002937755,0.002222918],"genre_scores_gemma":[0.9957372,0.0003898977,0.001324347,0.0000436153,0.00000669588,0.00001566763,0.0005600046,0.00002613707,0.00189649],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.00105383,"threshold_uncertainty_score":0.00464642,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01365079726372267,"score_gpt":0.2005308814453471,"score_spread":0.1868800841816244,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}