{"id":"W53925420","doi":"10.1023/a:1024445903306","title":"Imparting Bone Affinity to Glycoproteins Through the Conjugation of Bisphosphonates","year":2003,"lang":"en","type":"article","venue":"Pharmaceutical Research","topic":"Bone health and treatments","field":"Medicine","cited_by":27,"is_retracted":false,"has_abstract":false,"ca_institutions":"University of Calgary; University of Alberta","funders":"Canadian Institutes of Health Research; Killam Trusts; University of Alberta","keywords":"Fetuin; Conjugate; Chemistry; Conjugated system; Glycoprotein; Biochemistry; Stereochemistry; Organic chemistry; Polymer","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001791985,0.00009445276,0.0002093636,0.00006493063,0.0002284502,0.00001494466,0.00008185073,0.00005778976,0.0005078785],"category_scores_gemma":[0.002941028,0.00005986199,0.00005585862,0.0007114322,0.0002057813,0.00005345311,0.00005948576,0.0005402177,0.0002426822],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001482544,"about_ca_system_score_gemma":0.0003173854,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0007987748,"about_ca_topic_score_gemma":0.00002560807,"domain_scores_codex":[0.9977608,0.000316251,0.0003045161,0.0002203527,0.0007848332,0.0006132013],"domain_scores_gemma":[0.998185,0.0007496424,0.00003466665,0.000269279,0.0003581876,0.0004031575],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"theoretical_or_conceptual","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.01544532,0.008959789,0.1922262,0.002667365,0.0008357723,0.0005639657,0.009804817,0.00005822941,0.2453431,0.2963907,0.01826815,0.2094365],"study_design_scores_gemma":[0.003514702,0.0008745483,0.01352117,0.0001281124,0.00005987723,0.00004518466,0.0004061542,0.0002959701,0.8337414,0.004322186,0.1429767,0.0001139019],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9716976,0.001198831,0.0001097326,0.01208618,0.00007538365,0.001563224,0.00001001537,0.00002873197,0.01323028],"genre_scores_gemma":[0.9972737,0.00009042174,0.00103072,0.0009718853,0.00002317882,0.0001311925,0.000004293063,0.00001491022,0.0004597407],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.5883983,"threshold_uncertainty_score":0.5560913,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.291902652479819,"score_gpt":0.5406054231365311,"score_spread":0.2487027706567121,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}