{"id":"W563178998","doi":"10.71781/30004","title":"Development of cellular and gene therapies for b[beta]-Thalassemia and sickle cell disease","year":2008,"lang":"en","type":"dissertation","venue":"Open MIND","topic":"Hemoglobinopathies and Related Disorders","field":"Medicine","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"Canadian Institutes of Health Research; Université de Montréal","keywords":"Thalassemia; Disease; Beta thalassemia; Medicine; Biology; Bioinformatics; Genetics; Internal medicine","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":true,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002628749,0.0002501877,0.0001996625,0.0002344336,0.0002044693,0.0005140209,0.0002082185,0.0002895151,0.01886402],"category_scores_gemma":[0.000183624,0.00007341107,0.0001941972,0.0001496909,0.0002137671,0.0001938385,0.0001938481,0.0004478297,0.00204225],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003863502,"about_ca_system_score_gemma":0.001135278,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.002176398,"about_ca_topic_score_gemma":0.006851382,"domain_scores_codex":[0.9999439,0.000009075857,0.000002329877,0.000007798654,0.00002198364,0.00001498921],"domain_scores_gemma":[0.9999373,0.00001132964,0.000006164809,0.000002860089,0.00001993451,0.0000224015],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0005047823,0.0005467,0.000773282,0.001516086,0.00005172279,0.0003566865,0.0005664573,0.0005965502,0.2728673,0.02296508,0.05463568,0.6446197],"study_design_scores_gemma":[0.0002770475,0.001374346,0.005505943,0.000401909,0.00009986551,0.0005633839,0.0002271337,0.0003082062,0.1020594,0.003327411,0.8858428,0.00001263047],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"other","genre_scores_codex":[0.1708749,0.4446205,0.02101005,0.01711104,0.003860479,0.0007856757,0.002088533,0.0004304367,0.3392184],"genre_scores_gemma":[0.2901306,0.353821,0.01772749,0.002068168,0.0006269001,0.0003774131,0.001472585,0.00007183412,0.333704],"genre_candidate":"other","genre_consensus":null,"teacher_disagreement_score":0.01886402,"threshold_uncertainty_score":0.06310636,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01865831421407989,"score_gpt":0.275638069926234,"score_spread":0.2569797557121541,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}