{"id":"W563463152","doi":"10.1139/y06-012","title":"PTP1B and TC-PTP: novel roles in immune-cell signalingThis paper is one of a selection of papers published in this Special issue, entitled Second Messengers and Phosphoproteins—12th International Conference.","year":2006,"lang":"en","type":"review","venue":"Canadian Journal of Physiology and Pharmacology","topic":"Protein Tyrosine Phosphatases","field":"Biochemistry, Genetics and Molecular Biology","cited_by":49,"is_retracted":false,"has_abstract":true,"ca_institutions":"SickKids Foundation; McGill University Health Centre; Hospital for Sick Children","funders":"","keywords":"Protein tyrosine phosphatase; Immune system; Biology; Signal transduction; T cell; Cell biology; Immunology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":true,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000499811,0.0007867313,0.0009584845,0.001304139,0.0002707121,0.0008406538,0.0007150178,0.001119975,0.003102623],"category_scores_gemma":[0.0003185882,0.0002410064,0.0002171167,0.001566873,0.0004135794,0.001563582,0.0005579601,0.001243582,0.002679091],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0006157846,"about_ca_system_score_gemma":0.0007814874,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0006159915,"about_ca_topic_score_gemma":0.001241841,"domain_scores_codex":[0.9998639,0.00001466247,0.00001716623,0.00002949214,0.00005706512,0.00001764952],"domain_scores_gemma":[0.9998674,0.000036236,0.00002034764,0.000004159003,0.00004205455,0.00002969505],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.00008637683,0.00006302455,0.0002429967,0.005002635,0.00003666953,0.0004718682,0.00007364046,0.0003030705,0.006899837,0.004695027,0.02033932,0.9617856],"study_design_scores_gemma":[0.00002598427,0.00009579533,0.001131097,0.0007248973,0.00004338539,0.003012004,0.00007760517,0.0001087281,0.00149396,0.002454263,0.990815,0.00001715458],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.0003332813,0.9972737,0.0003249993,0.0003789625,0.0003649218,0.000004174128,0.00001078904,0.000009248573,0.001299958],"genre_scores_gemma":[0.001437159,0.9959885,0.000401362,0.0001977158,0.0003720479,0.000006049723,0.000025042,0.000001372041,0.001570678],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.003102623,"threshold_uncertainty_score":0.01037931,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01208658477610367,"score_gpt":0.2629631476151956,"score_spread":0.2508765628390919,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}