{"id":"W564708804","doi":"10.1007/s00401-015-1454-8","title":"Adult IDH wild type astrocytomas biologically and clinically resolve into other tumor entities","year":2015,"lang":"en","type":"article","venue":"Acta Neuropathologica","topic":"Glioma Diagnosis and Treatment","field":"Medicine","cited_by":278,"is_retracted":false,"has_abstract":false,"ca_institutions":"Princess Margaret Cancer Centre","funders":"Deutschen Konsortium für Translationale Krebsforschung","keywords":"Astrocytoma; Anaplastic astrocytoma; Pathology; Methylation; Biology; Cancer research; Glioma; Molecular pathology; Immunohistochemistry; Mutation; Medicine; Oncology; Gene; Genetics","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002887785,0.0002483874,0.000436327,0.00007638204,0.00008057638,0.00004763855,0.0001365623,0.0001178044,0.00007868074],"category_scores_gemma":[0.001738159,0.0001555497,0.00009337517,0.0001594282,0.0002639243,0.00006574624,0.000182259,0.0002328061,0.0001512843],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00002855272,"about_ca_system_score_gemma":0.00005372045,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00002044444,"about_ca_topic_score_gemma":0.000005400773,"domain_scores_codex":[0.998367,0.0001803394,0.0003910666,0.0005268646,0.0002226018,0.0003121519],"domain_scores_gemma":[0.9987143,0.0001873051,0.0001439208,0.0003987096,0.0002413761,0.0003143313],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.00284557,0.002058952,0.8905362,0.00005543419,0.0001121849,0.009670109,0.0008194278,0.000001727894,0.0635497,0.0007182153,0.02282405,0.006808372],"study_design_scores_gemma":[0.008487148,0.02847999,0.8270243,0.0002069701,0.0004263154,0.003067997,0.0007523601,0.00006665968,0.005913895,0.001363223,0.1234577,0.0007534529],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.991659,0.0005403509,0.000006112762,0.002528439,0.0002094474,0.0003254167,0.000009242316,0.0001676784,0.004554314],"genre_scores_gemma":[0.9891225,0.0002985224,0.004136152,0.006061669,0.0001519157,0.00003598079,0.00001398878,0.00002608546,0.0001531902],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.1006337,"threshold_uncertainty_score":0.6343133,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.04472792800836908,"score_gpt":0.3025950285431996,"score_spread":0.2578671005348306,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}