{"id":"W564708804","doi":"10.1007/s00401-015-1454-8","title":"Adult IDH wild type astrocytomas biologically and clinically resolve into other tumor entities","year":2015,"lang":"en","type":"article","venue":"Acta Neuropathologica","topic":"Glioma Diagnosis and Treatment","field":"Medicine","cited_by":278,"is_retracted":false,"has_abstract":false,"ca_institutions":"Princess Margaret Cancer Centre","funders":"Deutschen Konsortium für Translationale Krebsforschung","keywords":"Astrocytoma; Anaplastic astrocytoma; Pathology; Methylation; Biology; Cancer research; Glioma; Molecular pathology; Immunohistochemistry; Mutation; Medicine; Oncology; Gene; Genetics","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002620199,0.0005802944,0.0004912704,0.0009653075,0.0005565064,0.0009938646,0.000317952,0.0005824832,0.001707381],"category_scores_gemma":[0.0009479315,0.0002075694,0.0003966618,0.0007321545,0.0006066253,0.001168854,0.0006280536,0.0006964487,0.001766079],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004881884,"about_ca_system_score_gemma":0.0005501912,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001066538,"about_ca_topic_score_gemma":0.002006537,"domain_scores_codex":[0.9997541,0.00002119245,0.00003799085,0.00004971659,0.00005566379,0.00008130656],"domain_scores_gemma":[0.9994368,0.00005373825,0.0002030836,0.00007850281,0.0001034231,0.000124352],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.001136499,0.000218472,0.5270494,0.00028018,0.0001495693,0.1081892,0.001503438,0.0009544504,0.1193703,0.006434451,0.007414187,0.2272999],"study_design_scores_gemma":[0.00007042248,0.0007774809,0.5033867,0.0001696338,0.0001940679,0.4163703,0.002633499,0.002287105,0.02449537,0.007131021,0.04242534,0.00005894347],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9584404,0.00605536,0.007036332,0.0007774224,0.0002788004,0.0001082417,0.0006916094,0.0005381074,0.02607363],"genre_scores_gemma":[0.9896825,0.00198642,0.004087855,0.0002958655,0.0001423681,0.00002187291,0.0009951513,0.00006821247,0.002719779],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001707381,"threshold_uncertainty_score":0.005711734,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.04472792800836908,"score_gpt":0.3025950285431996,"score_spread":0.2578671005348306,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}