{"id":"W57359236","doi":"10.1177/070674370705200108","title":"Definition, Assessment, and Staging of Treatment—Resistant Refractory Major Depression: A Review of Current Concepts and Methods","year":2007,"lang":"en","type":"review","venue":"The Canadian Journal of Psychiatry","topic":"Treatment of Major Depression","field":"Medicine","cited_by":404,"is_retracted":false,"has_abstract":true,"ca_institutions":"McGill University; Douglas Mental Health University Institute","funders":"","keywords":"PsycINFO; MEDLINE; Treatment-resistant depression; Depression (economics); Medicine; Comorbidity; Psychiatry; Systematic review; Psychology; Intensive care medicine; Clinical psychology; Major depressive disorder; Cognition","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":true,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.02259375,0.002286348,0.004023489,0.01631051,0.0007466457,0.004103389,0.003220405,0.002026035,0.001488819],"category_scores_gemma":[0.03471895,0.001006139,0.001943448,0.01032466,0.00376011,0.00469668,0.001286218,0.002397552,0.0004937106],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.004371378,"about_ca_system_score_gemma":0.007713076,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.004178968,"about_ca_topic_score_gemma":0.006802927,"domain_scores_codex":[0.9878557,0.005545386,0.003774152,0.0008718551,0.001816942,0.0001360053],"domain_scores_gemma":[0.9610964,0.02921886,0.005692665,0.0004742344,0.003218471,0.000299363],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.000166128,0.0001341809,0.005207299,0.1192004,0.0006362456,0.0002247176,0.0006987574,0.0004167001,0.0002485849,0.005669332,0.0134302,0.8539674],"study_design_scores_gemma":[0.000325877,0.000799322,0.03695089,0.5850448,0.004399154,0.006865699,0.003622928,0.001974241,0.0006232997,0.02094537,0.338134,0.0003145525],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.0001425913,0.9976584,0.0005820093,0.00116248,0.0001580874,0.00004471946,0.00002495128,0.000006861883,0.0002199778],"genre_scores_gemma":[0.003222071,0.9911692,0.004197965,0.0007659055,0.0003383963,0.0001691447,0.00006220853,0.000005059401,0.0000700319],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.02259375,"threshold_uncertainty_score":0.1194886,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.1182667920859504,"score_gpt":0.4804197970765894,"score_spread":0.3621530049906391,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}