{"id":"W58274838","doi":"","title":"Enhancing alkylating agent resistance through ERCC2 gene transfection in human glioma cell line.","year":2003,"lang":"en","type":"article","venue":"PubMed","topic":"RNA Interference and Gene Delivery","field":"Biochemistry, Genetics and Molecular Biology","cited_by":2,"is_retracted":false,"has_abstract":true,"ca_institutions":"McGill University","funders":"","keywords":"Transfection; ERCC2; Cell culture; Melphalan; Glioma; Molecular biology; Cytotoxicity; Biology; Western blot; Cancer research; DNA repair; Gene; Chemistry; In vitro; Genetics; Chemotherapy; Nucleotide excision repair","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002169452,0.0004530125,0.0004576698,0.0002530579,0.0001376689,0.0002377325,0.0001926317,0.0002979053,0.001119328],"category_scores_gemma":[0.0001683724,0.000107363,0.0002745201,0.0002855185,0.0001741522,0.0001786659,0.0001174032,0.0003940118,0.0004788344],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002986037,"about_ca_system_score_gemma":0.0002665732,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001329824,"about_ca_topic_score_gemma":0.001696419,"domain_scores_codex":[0.9997837,0.00004069123,0.00002471593,0.00003859312,0.00007729141,0.00003506128],"domain_scores_gemma":[0.9999094,0.00002177961,0.00001876274,0.00001638308,0.00002399073,0.000009767831],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00008068982,0.00003925681,0.0001303382,0.00006063068,0.000006726144,0.00005065647,0.0000132941,0.00003851848,0.9981908,0.00005122119,0.0001003229,0.001237447],"study_design_scores_gemma":[0.00002562737,0.0003996601,0.001303405,0.000003361374,0.00002767081,0.000314855,0.000008977591,0.0003495666,0.9944975,0.00001101829,0.003055301,0.000003157622],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9810452,0.005712454,0.00854607,0.0003012256,0.00009196153,0.0002101258,0.001188759,0.0002997509,0.002604506],"genre_scores_gemma":[0.9792774,0.003280456,0.01146486,0.00009057041,0.0000246108,0.0001580424,0.002438136,0.00004094368,0.003224916],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001329824,"threshold_uncertainty_score":0.003744483,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01925098665743902,"score_gpt":0.2354797205823363,"score_spread":0.2162287339248973,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}