{"id":"W59493982","doi":"10.1385/1-59259-958-3:161","title":"Synthetic Lethal Screen","year":2005,"lang":"en","type":"article","venue":"Humana Press eBooks","topic":"Fungal and yeast genetics research","field":"Biochemistry, Genetics and Molecular Biology","cited_by":14,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Saskatchewan","funders":"Canadian Institutes of Health Research","keywords":"Plasmid; Mutant; Biology; Mutagenesis; Gene; Genetics; Mutation; Lethal allele; Molecular biology","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001186301,0.0001243694,0.00009165084,0.00002962376,0.00009279726,0.00003734288,0.0002882734,0.0001000863,0.00005726485],"category_scores_gemma":[0.00001896935,0.0001156489,0.00007247401,0.00000760782,0.0001062387,0.000001332655,0.0002122263,0.0001048545,0.00005264992],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000007431854,"about_ca_system_score_gemma":0.00002728773,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00005584873,"about_ca_topic_score_gemma":0.00006128423,"domain_scores_codex":[0.9990253,0.00004953971,0.0001308326,0.0003089837,0.0001858118,0.0002995054],"domain_scores_gemma":[0.9993861,0.000006505833,0.00002683751,0.0004186318,0.00005480301,0.0001071212],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0001381005,0.00008963486,0.00003808442,0.00003531496,0.00010198,0.00001347158,0.0001384851,0.0002274297,0.7740158,0.003678781,0.01166906,0.2098539],"study_design_scores_gemma":[0.0002526777,0.0001041517,0.0001227922,0.000007488427,0.000008149744,0.00001180062,0.000006037051,0.0001354251,0.4724987,0.00003789858,0.5266702,0.0001446579],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.5096005,0.008594439,0.0005260142,0.0001291969,0.0001176215,0.0003694725,0.00003763868,0.00004770694,0.4805774],"genre_scores_gemma":[0.9692791,0.0001150318,0.0004887677,0.0001428678,0.000633116,0.00002817619,0.00002387084,0.00002660813,0.02926249],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.5150011,"threshold_uncertainty_score":0.4716027,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.04344153872393784,"score_gpt":0.2958754454690409,"score_spread":0.252433906745103,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}