{"id":"W59493982","doi":"10.1385/1-59259-958-3:161","title":"Synthetic Lethal Screen","year":2005,"lang":"en","type":"article","venue":"Humana Press eBooks","topic":"Fungal and yeast genetics research","field":"Biochemistry, Genetics and Molecular Biology","cited_by":14,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Saskatchewan","funders":"Canadian Institutes of Health Research","keywords":"Plasmid; Mutant; Biology; Mutagenesis; Gene; Genetics; Mutation; Lethal allele; Molecular biology","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001139832,0.001928458,0.00238512,0.002915329,0.001307113,0.001390261,0.002255105,0.001407444,0.03026491],"category_scores_gemma":[0.00136234,0.0006427952,0.001408668,0.001292789,0.0006773362,0.0005024689,0.002030355,0.001887328,0.02446507],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0007502778,"about_ca_system_score_gemma":0.001027597,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001301517,"about_ca_topic_score_gemma":0.002307212,"domain_scores_codex":[0.9974717,0.0003915098,0.0002233633,0.0004544541,0.001140175,0.0003188234],"domain_scores_gemma":[0.9987922,0.0002546125,0.0001170617,0.0002692218,0.0003634592,0.0002034202],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0004735611,0.0006044062,0.001661859,0.000629428,0.000102298,0.0010872,0.0001838999,0.0006098488,0.9253141,0.004236485,0.02287614,0.04222079],"study_design_scores_gemma":[0.0001235832,0.001066994,0.00709271,0.0001671044,0.0002027803,0.003423629,0.0001882561,0.002068383,0.6210221,0.001656822,0.3628271,0.0001605954],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"methods","genre_gemma":"empirical","genre_scores_codex":[0.2221644,0.008788611,0.3775464,0.003212621,0.001642673,0.009927752,0.1303286,0.02972885,0.2166601],"genre_scores_gemma":[0.2776538,0.009413435,0.1684718,0.002113051,0.0001474958,0.00502551,0.1986408,0.00500524,0.3335287],"genre_candidate":"empirical","genre_consensus":null,"teacher_disagreement_score":0.03026491,"threshold_uncertainty_score":0.1012462,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.04344153872393784,"score_gpt":0.2958754454690409,"score_spread":0.252433906745103,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}