{"id":"W595689193","doi":"","title":"α2Macroglobulin differentially regulates ligand-dependent p75 and TrkA receptor activation ex vivo and in retina","year":2015,"lang":"en","type":"article","venue":"Investigative Ophthalmology & Visual Science","topic":"Retinal Diseases and Treatments","field":"Medicine","cited_by":0,"is_retracted":false,"has_abstract":false,"ca_institutions":"McGill University; Jewish General Hospital","funders":"","keywords":"Ex vivo; Tropomyosin receptor kinase A; Cell biology; Low-affinity nerve growth factor receptor; Retina; Receptor; Chemistry; Ligand (biochemistry); In vivo; Neuroscience; Biology; Neurotrophin; Biochemistry; Genetics","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003007362,0.0003303171,0.0003407963,0.0005954247,0.0004242156,0.0008072223,0.0003738489,0.0003777065,0.001954584],"category_scores_gemma":[0.0003082232,0.0002519178,0.0005670032,0.0003750256,0.0004283954,0.0005481427,0.0003198769,0.001205666,0.0009824589],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0009891801,"about_ca_system_score_gemma":0.0005348639,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.004320452,"about_ca_topic_score_gemma":0.005418064,"domain_scores_codex":[0.9995778,0.00006856702,0.00002963618,0.00005698507,0.00007522417,0.0001917132],"domain_scores_gemma":[0.9997794,0.00003718102,0.00004105817,0.00004040983,0.00003484814,0.00006721008],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0003157724,0.00002373066,0.0001050707,0.00001848611,0.000006126582,0.00003827212,0.00002849567,0.00001988926,0.9989906,0.00007803388,0.00004547602,0.0003300926],"study_design_scores_gemma":[0.00005221026,0.0002607901,0.01741654,0.00001095936,0.00004625661,0.0002211256,0.000227315,0.0008340356,0.9789128,0.00008738888,0.001919837,0.00001096045],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9940301,0.001852371,0.001679527,0.0001531328,0.0000594615,0.00001790847,0.0004468687,0.00004267505,0.001717816],"genre_scores_gemma":[0.9901218,0.0009645763,0.001093353,0.0001213936,0.00002829192,0.00004478859,0.0009711973,0.00004593506,0.006608766],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.004320452,"threshold_uncertainty_score":0.008590579,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.04206610499547831,"score_gpt":0.3396484863229107,"score_spread":0.2975823813274324,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}