{"id":"W59810833","doi":"10.69645/nmfu7892","title":"Genetic, environmental and other design issues relevant for pharmacogenetics studies","year":2007,"lang":"en","type":"article","venue":"The biomedical & life sciences collection.","topic":"Genetics, Bioinformatics, and Biomedical Research","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"McGill University","funders":"","keywords":"Pharmacogenetics; Computational biology; Biology; Genetics; Genotype; Gene","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.006843813,0.001053017,0.001076676,0.0007924454,0.000694157,0.001646332,0.001529046,0.00372145,0.1850782],"category_scores_gemma":[0.01303759,0.0008803504,0.0008700022,0.0004611907,0.0007842813,0.001201356,0.001377046,0.002085582,0.06342854],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0006656509,"about_ca_system_score_gemma":0.001002035,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000464011,"about_ca_topic_score_gemma":0.00130069,"domain_scores_codex":[0.9970888,0.001333617,0.0002465226,0.0001861495,0.0008841946,0.0002606669],"domain_scores_gemma":[0.9911892,0.005141241,0.0004953318,0.001253798,0.001085254,0.00083508],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"not_applicable","study_design_gemma":"theoretical_or_conceptual","study_design_scores_codex":[0.003325791,0.0009267102,0.003002669,0.001860658,0.0001546745,0.00257009,0.0005154838,0.00173245,0.1231384,0.01865807,0.4764781,0.3676369],"study_design_scores_gemma":[0.0007656422,0.001145384,0.00253356,0.0002601647,0.000252404,0.002395617,0.0002053655,0.00164894,0.05092913,0.01457167,0.9251819,0.0001101115],"study_design_candidate":"theoretical_or_conceptual","study_design_consensus":null,"genre_codex":"methods","genre_gemma":"methods","genre_scores_codex":[0.02836734,0.005895855,0.507073,0.06935775,0.01687043,0.01538202,0.01400288,0.0181042,0.3249466],"genre_scores_gemma":[0.1471947,0.006209868,0.361959,0.04047382,0.006548549,0.01374633,0.007266284,0.008277155,0.4083243],"genre_candidate":"methods","genre_consensus":"methods","teacher_disagreement_score":0.1850782,"threshold_uncertainty_score":0.6191484,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.04843387707442619,"score_gpt":0.3506463367561041,"score_spread":0.3022124596816779,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}