{"id":"W599211393","doi":"10.1007/s11906-015-0568-7","title":"Endothelin Receptor Antagonists: New Hope for Renal Protection?","year":2015,"lang":"en","type":"review","venue":"Current Hypertension Reports","topic":"Nitric Oxide and Endothelin Effects","field":"Medicine","cited_by":11,"is_retracted":false,"has_abstract":false,"ca_institutions":"NOSM University; University of Toronto; Sunnybrook Health Science Centre","funders":"","keywords":"Medicine; Endothelin receptor; Proteinuria; Kidney disease; Nephrology; Clinical trial; Internal medicine; Endothelin receptor antagonist; Peripheral edema; Fibrosis; Diabetic nephropathy; Endothelins; Kidney; Pharmacology; Receptor; Adverse effect","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0008232449,0.0006207515,0.002240435,0.0008980232,0.0002433317,0.001193142,0.0009285645,0.001386966,0.004979821],"category_scores_gemma":[0.001034108,0.0002094435,0.0005317802,0.000881725,0.0006061624,0.001711652,0.0006300422,0.003139632,0.001932359],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003005333,"about_ca_system_score_gemma":0.0007376992,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0003854366,"about_ca_topic_score_gemma":0.001197867,"domain_scores_codex":[0.9998171,0.00003916892,0.00003339584,0.00003454925,0.00005526929,0.00002050242],"domain_scores_gemma":[0.9994888,0.0002840688,0.00006629384,0.00001626453,0.00009122919,0.00005325088],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0004078286,0.000130435,0.0002975273,0.01585474,0.000273242,0.0002853852,0.00006481445,0.0001776096,0.002603481,0.004282346,0.05096431,0.9246584],"study_design_scores_gemma":[0.0001818966,0.0002932887,0.001311621,0.00439897,0.0004854412,0.001220255,0.0001020895,0.0001162419,0.0005713679,0.003726776,0.9875551,0.00003706207],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.0001048208,0.9981107,0.0001043021,0.0008243747,0.0003893197,0.000001976956,0.00001859122,0.000006937615,0.000438986],"genre_scores_gemma":[0.0009713727,0.9968785,0.0001692784,0.0008012056,0.0007287738,0.000004135296,0.00002638124,0.000001614209,0.000418613],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.004979821,"threshold_uncertainty_score":0.01665914,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.1475899714737354,"score_gpt":0.3751185838332859,"score_spread":0.2275286123595506,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}