{"id":"W59929109","doi":"10.1007/978-1-4419-6673-5_3","title":"Maintenance of Hox Gene Expression Patterns","year":2010,"lang":"en","type":"review","venue":"Advances in experimental medicine and biology","topic":"Epigenetics and DNA Methylation","field":"Biochemistry, Genetics and Molecular Biology","cited_by":20,"is_retracted":false,"has_abstract":false,"ca_institutions":"University of British Columbia","funders":"","keywords":"Hox gene; Homeotic gene; Polycomb-group proteins; Biology; Gene silencing; Enhancer; Epigenetics; Genetics; Transcription factor; Gene; Transcription (linguistics); BMI1; Chromatin; Cell biology; Repressor","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0006073803,0.0006455791,0.0009973481,0.0007487012,0.0002253235,0.001036357,0.001058335,0.0006908723,0.001324745],"category_scores_gemma":[0.0003663448,0.0002809171,0.0002309577,0.0009049532,0.00115961,0.0007998591,0.0007067382,0.00128205,0.001139514],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0008678648,"about_ca_system_score_gemma":0.0007747363,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0008768096,"about_ca_topic_score_gemma":0.001301427,"domain_scores_codex":[0.9997929,0.00002594666,0.00001651107,0.00005671862,0.00007925985,0.00002863504],"domain_scores_gemma":[0.9998705,0.00004039417,0.00002248392,0.00001625393,0.00003610004,0.00001417166],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.00009790163,0.00002639622,0.0006739778,0.00338419,0.00004661309,0.0003828687,0.00009992801,0.0006979742,0.0864929,0.01873216,0.007962534,0.8814027],"study_design_scores_gemma":[0.00002639374,0.00006225633,0.005148988,0.0005809224,0.00009125152,0.002195755,0.0001594992,0.0003812932,0.05571043,0.005866219,0.9297478,0.00002927847],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.004155531,0.9760945,0.009159188,0.0009180158,0.0006413222,0.00002044078,0.0001178454,0.00009185645,0.008801194],"genre_scores_gemma":[0.02828146,0.9574559,0.003916104,0.000457715,0.000384136,0.00003937944,0.0002514725,0.00002090732,0.009193034],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.001324745,"threshold_uncertainty_score":0.006296813,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03404979479685621,"score_gpt":0.3990870597453416,"score_spread":0.3650372649484854,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}