{"id":"W5995330","doi":"10.1007/3-540-30657-9_5","title":"IgA Adaptation to the Presence of Commensal Bacteria in the Intestine","year":2006,"lang":"en","type":"review","venue":"Current topics in microbiology and immunology","topic":"Gut microbiota and health","field":"Biochemistry, Genetics and Molecular Biology","cited_by":56,"is_retracted":false,"has_abstract":false,"ca_institutions":"McMaster University Medical Centre","funders":"","keywords":"Biology; Colonisation; Immune system; Commensalism; Secretion; Microbiology; Bacteria; Lymphatic system; Mesenteric lymph nodes; Intestinal mucosa; Flora (microbiology); Immunology; Adaptation (eye); Segmented filamentous bacteria; Immunoglobulin A; Immunity; Mucosal immunity; Colonization; Immunoglobulin G; Medicine","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0006391701,0.0008581892,0.001804392,0.0008489002,0.0002068595,0.001067338,0.001054199,0.001354704,0.00148504],"category_scores_gemma":[0.0005470604,0.0002087248,0.0002960085,0.001242406,0.0005383719,0.001027271,0.0005671478,0.001195772,0.001407865],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004924769,"about_ca_system_score_gemma":0.0007268317,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0005467416,"about_ca_topic_score_gemma":0.0008801243,"domain_scores_codex":[0.9998436,0.00002591178,0.0000186209,0.00003946957,0.00005459881,0.00001781189],"domain_scores_gemma":[0.9997297,0.00009743698,0.00004738398,0.00001078693,0.00007161683,0.00004298922],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0002210547,0.0000513032,0.0004381239,0.007191868,0.00007044516,0.0004474201,0.00003980751,0.0002555313,0.00926885,0.001250241,0.0112913,0.9694742],"study_design_scores_gemma":[0.00008037435,0.0003706972,0.008296191,0.00248002,0.0002828082,0.004152718,0.0002013198,0.0002585052,0.006197965,0.003369812,0.9742622,0.00004737481],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.0006667731,0.9972245,0.0004215317,0.0003833057,0.0004519965,0.000003768818,0.00001294284,0.00001326036,0.0008219689],"genre_scores_gemma":[0.002145429,0.9958293,0.0004288257,0.0002230948,0.0004041849,0.000006321426,0.00002136707,0.000001779746,0.0009397485],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.001804392,"threshold_uncertainty_score":0.004967988,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.04483931910205388,"score_gpt":0.3395029398047933,"score_spread":0.2946636207027394,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}