{"id":"W606545495","doi":"10.1016/j.imlet.2015.06.006","title":"Clinical grade expansion of MSCs","year":2015,"lang":"en","type":"article","venue":"Immunology Letters","topic":"Mesenchymal stem cell research","field":"Medicine","cited_by":50,"is_retracted":false,"has_abstract":false,"ca_institutions":"","funders":"Ministry of Health, British Columbia; Ministero della Salute","keywords":"Mesenchymal stem cell; Platelet lysate; Good manufacturing practice; Umbilical cord; Bone marrow; Medicine; Stromal cell; Clinical Practice; Cell therapy; Fetal bovine serum; Immunology; Cell; Biomedical engineering; Biotechnology; Cancer research; Chemistry; Pathology; Biology; Biochemistry","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0008516188,0.0004509462,0.0003730534,0.0008753805,0.0004054721,0.001064669,0.0003879098,0.0008168684,0.009228019],"category_scores_gemma":[0.001014114,0.0002236423,0.0004015871,0.0005084993,0.0003382589,0.0003722188,0.0005385089,0.001362087,0.005620796],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003440096,"about_ca_system_score_gemma":0.0006825461,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0004571853,"about_ca_topic_score_gemma":0.001152776,"domain_scores_codex":[0.9992633,0.00009472336,0.0001144065,0.0001379224,0.0002872847,0.0001023458],"domain_scores_gemma":[0.9994889,0.00006377668,0.00003736477,0.0001102741,0.0001951552,0.0001043788],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.001309718,0.00106327,0.008378037,0.0004007123,0.0000473153,0.001518571,0.0003302793,0.000476402,0.842714,0.003686811,0.01452257,0.1255523],"study_design_scores_gemma":[0.0005032224,0.004594249,0.01969867,0.0002038493,0.0002401828,0.006137892,0.0002888906,0.002506402,0.7825071,0.002174663,0.1811109,0.0000340228],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.7787879,0.01263335,0.04510552,0.00606677,0.002985659,0.005230074,0.003505795,0.002070877,0.1436141],"genre_scores_gemma":[0.9132496,0.00428102,0.0261678,0.003056667,0.0008313069,0.001081291,0.008783392,0.0003105138,0.0422385],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.009228019,"threshold_uncertainty_score":0.0308708,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.1284562147751833,"score_gpt":0.4048374890341732,"score_spread":0.2763812742589899,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}