{"id":"W60915718","doi":"10.1161/circ.118.suppl_18.s_560-c","title":"Abstract 5493: Heparan-Sulfate Deficient Perlecan Mice Exhibit Increased Vascular Smooth Muscle Cell Activity and Response to Arterial Injury","year":2008,"lang":"en","type":"article","venue":"Circulation","topic":"Angiogenesis and VEGF in Cancer","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Toronto","funders":"","keywords":"Perlecan; Medicine; Heparan sulfate; Restenosis; Vascular smooth muscle; Intimal hyperplasia; Internal medicine; Endocrinology; Heparin; Smooth muscle","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002345357,0.001290598,0.0005626163,0.001125892,0.0003829627,0.0005573265,0.0004422714,0.001239479,0.01114316],"category_scores_gemma":[0.0001244134,0.0005011621,0.0005987569,0.0003700242,0.0007804835,0.0004148827,0.0003799068,0.002575972,0.00254642],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004591685,"about_ca_system_score_gemma":0.0002456808,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0008341431,"about_ca_topic_score_gemma":0.0009317035,"domain_scores_codex":[0.9994962,0.00005085373,0.0000684785,0.0001476666,0.000131213,0.0001055248],"domain_scores_gemma":[0.9993761,0.00003243676,0.000228384,0.00003544878,0.00004235572,0.0002851819],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0004694931,0.0001144356,0.0002760273,0.00004721316,0.00001356297,0.0001974933,0.0000271474,0.000030293,0.9975811,0.00009831832,0.0001739538,0.0009709206],"study_design_scores_gemma":[0.0002697962,0.002382309,0.039318,0.0000855804,0.0001183507,0.004095086,0.0002634742,0.001117138,0.9452061,0.0003257089,0.006773791,0.00004472384],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9899818,0.0007232535,0.002841523,0.0004165288,0.0001412713,0.00005060171,0.003144972,0.0003563171,0.002343718],"genre_scores_gemma":[0.9664754,0.0009243202,0.004367212,0.0003925069,0.00007769297,0.0002170964,0.003299984,0.0002664542,0.02397932],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.01114316,"threshold_uncertainty_score":0.03727752,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01243833451967228,"score_gpt":0.2390288341966454,"score_spread":0.2265904996769731,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}