{"id":"W6101351","doi":"10.1007/978-1-4615-0453-5_5","title":"Functional Significance of Ryanodine Receptor-Mediated Calcium Leaks in Sarcoplasmic Reticulum Membranes","year":2004,"lang":"en","type":"book-chapter","venue":"Progress in experimental cardiology","topic":"Cardiac electrophysiology and arrhythmias","field":"Medicine","cited_by":0,"is_retracted":false,"has_abstract":false,"ca_institutions":"University of Manitoba; St. Boniface Hospital","funders":"","keywords":"Ryanodine receptor; Endoplasmic reticulum; Biophysics; Chemistry; Cell biology; Membrane; Calcium; Biochemistry; Biology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0002025703,0.0005126704,0.001787413,0.0004203118,0.00003591882,0.000003610294,0.0001240137,0.0009608126,0.0006081474],"category_scores_gemma":[0.00003486011,0.000498313,0.0004370054,0.0001096745,0.001243752,0.00004361981,0.0001143163,0.001005612,0.00008812371],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0006028947,"about_ca_system_score_gemma":0.0003663581,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00002469457,"about_ca_topic_score_gemma":0.000004947468,"domain_scores_codex":[0.9975147,0.0001135822,0.0007695283,0.0007826498,0.0003019082,0.000517686],"domain_scores_gemma":[0.9990008,0.0001275544,0.0002648812,0.0004057181,0.00009350268,0.000107581],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.03898126,0.001894137,0.0577364,0.003518662,0.004575187,0.01845668,0.002132962,0.002699815,0.7773114,0.07919478,0.00642578,0.007072928],"study_design_scores_gemma":[0.03877179,0.01229145,0.03477109,0.005032995,0.0007354653,0.006767879,0.0008450928,0.0001109838,0.844951,0.007051015,0.04373785,0.004933436],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.7190588,0.1219141,0.00001119808,0.0007223784,0.003034332,0.003521211,0.0002161672,0.0001910309,0.1513308],"genre_scores_gemma":[0.9927341,0.0007871938,0.0001185092,0.0001186196,0.0006316579,0.0002862297,0.0007839484,0.00008409913,0.004455589],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.2736754,"threshold_uncertainty_score":0.9997469,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01955479791025705,"score_gpt":0.275239213345482,"score_spread":0.2556844154352249,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}