{"id":"W62169709","doi":"10.1161/circ.120.suppl_18.s1082","title":"Abstract 5309: Perforin-Independent Granzyme B-Mediated Extracellular Matrix Protein Cleavage Contributes to Abdominal Aortic Aneurysm","year":2009,"lang":"en","type":"article","venue":"Circulation","topic":"Aortic aneurysm repair treatments","field":"Medicine","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of British Columbia","funders":"","keywords":"Granzyme B; Perforin; Extracellular matrix; Granzyme; Medicine; Apolipoprotein E; Abdominal aortic aneurysm; Extracellular; Aortic aneurysm; Aorta; Aneurysm; Pathology; Immunology; Immune system; Internal medicine; Cell biology; Biology; CD8; Surgery","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000164067,0.0007797558,0.0003711143,0.0003192739,0.000196642,0.0003488293,0.0003261431,0.0005792304,0.004661737],"category_scores_gemma":[0.0001429061,0.0002047446,0.0003523877,0.0001682114,0.0003600835,0.000231298,0.0003206637,0.001036209,0.001742163],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001955622,"about_ca_system_score_gemma":0.0001526249,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0001572247,"about_ca_topic_score_gemma":0.0001022011,"domain_scores_codex":[0.9999021,0.00001428931,0.00001554056,0.00002324452,0.00002068257,0.00002413071],"domain_scores_gemma":[0.9998142,0.00002143995,0.00006713682,0.00001543046,0.00001524568,0.00006663488],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.002740481,0.0002565278,0.003003753,0.0003158986,0.00002315144,0.002677346,0.00003551643,0.00008970002,0.9847404,0.0002780544,0.0008770138,0.004962222],"study_design_scores_gemma":[0.00110649,0.003893349,0.1982261,0.0002206081,0.0003955027,0.04251566,0.0003065441,0.003404111,0.7257202,0.001155935,0.02301476,0.00004078895],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9881689,0.002743446,0.002628302,0.0006095318,0.0002230784,0.0000793925,0.001004972,0.0001319534,0.004410343],"genre_scores_gemma":[0.9846222,0.003729424,0.001990299,0.0003448632,0.0002720522,0.0001100733,0.001407196,0.00004631691,0.007477569],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.004661737,"threshold_uncertainty_score":0.01559508,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01311307603083438,"score_gpt":0.2726476750000093,"score_spread":0.2595345989691749,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}