{"id":"W62825085","doi":"10.1096/fasebj.21.6.a772","title":"Conversion of cardiac myocytes to a proinflammtory phenotype in sepsis: role of peroxynitrite derived from eNOS","year":2007,"lang":"en","type":"article","venue":"The FASEB Journal","topic":"Neutrophil, Myeloperoxidase and Oxidative Mechanisms","field":"Immunology and Microbiology","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"Western University; London Health Sciences Centre; Lawson Health Research Institute","funders":"","keywords":"Peroxynitrite; Myocyte; Proinflammatory cytokine; Enos; Sepsis; Chemistry; Internal medicine; Inflammation; Immunology; Endocrinology; Medicine; Nitric oxide; Biochemistry; Nitric oxide synthase; Superoxide; Enzyme","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002852078,0.0003717581,0.000268427,0.0001149603,0.0001351292,0.0002296474,0.0001002058,0.0002589643,0.001000577],"category_scores_gemma":[0.0001262117,0.0001163198,0.0001747743,0.00006220181,0.0002307849,0.0002245283,0.000203636,0.0006691613,0.00019213],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00007904859,"about_ca_system_score_gemma":0.0001159662,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00007174817,"about_ca_topic_score_gemma":0.0001397614,"domain_scores_codex":[0.9998603,0.00003653967,0.00001920346,0.00002788386,0.0000277301,0.00002835569],"domain_scores_gemma":[0.9998945,0.00001344606,0.00003479228,0.00001000416,0.00001049528,0.00003670063],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001608042,0.00002343158,0.0001760467,0.00001887552,0.000002197595,0.00005431038,0.00001331735,0.000007531119,0.999244,0.00002412027,0.000006363175,0.0002691153],"study_design_scores_gemma":[0.00007058254,0.00157902,0.02965693,0.00002044027,0.00002615547,0.000730975,0.000198377,0.0005348573,0.9660676,0.0001135497,0.000995428,0.000006109006],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.996628,0.001067683,0.001588509,0.0001015496,0.00003178665,0.00002134109,0.00008482819,0.00001323976,0.000463108],"genre_scores_gemma":[0.9947973,0.001014677,0.002011824,0.00009242547,0.00002334525,0.00004992194,0.000226562,0.000007182218,0.001776647],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001000577,"threshold_uncertainty_score":0.003347278,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.00976015850755826,"score_gpt":0.2210876016430685,"score_spread":0.2113274431355102,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}