{"id":"W62980418","doi":"","title":"Induction of IRF-3 and IRF-7 phosphorylation following activation of the RIG-I pathway.","year":2006,"lang":"en","type":"article","venue":"PubMed","topic":"interferon and immune responses","field":"Immunology and Microbiology","cited_by":94,"is_retracted":false,"has_abstract":true,"ca_institutions":"Terry Fox Research Institute","funders":"","keywords":"TRIF; Interferon regulatory factors; Signal transducing adaptor protein; Phosphorylation; RIG-I; Biology; Signal transduction; IRF3; Interferon; Cell biology; Innate immune system; NS3; Kinase; Molecular biology; Virology; Receptor; Toll-like receptor; Virus; Biochemistry; Hepatitis C virus","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001744395,0.0004689682,0.0001885544,0.0002233793,0.0001301929,0.0001915787,0.0001581871,0.0002452481,0.00242825],"category_scores_gemma":[0.00009334662,0.0001281383,0.0005024152,0.0001139298,0.0001836844,0.0002071844,0.0002575669,0.0006143141,0.001087058],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002830931,"about_ca_system_score_gemma":0.0001995342,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0002350829,"about_ca_topic_score_gemma":0.0003264233,"domain_scores_codex":[0.9998322,0.00003217968,0.00001090811,0.00002514569,0.00003414016,0.00006547684],"domain_scores_gemma":[0.999912,0.00001420893,0.00002505431,0.00001538999,0.00001128229,0.00002203943],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001368565,0.00001815027,0.0001173877,0.00005140266,0.000004551746,0.0000410235,0.000009705956,0.00002303676,0.9985511,0.00009306736,0.00003644396,0.0009172595],"study_design_scores_gemma":[0.0000154849,0.0001539002,0.004146366,0.000009735183,0.00001127196,0.0002567154,0.00001791317,0.0003998296,0.9930059,0.00009122401,0.001887361,0.00000436805],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9868873,0.003622839,0.004155655,0.0001669859,0.00009393191,0.0000709065,0.001062007,0.0001468215,0.003793767],"genre_scores_gemma":[0.9899711,0.001341418,0.003307152,0.00008127916,0.00001996171,0.00006547865,0.002002377,0.00002040374,0.003190809],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.00242825,"threshold_uncertainty_score":0.008123338,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.0103670876252009,"score_gpt":0.1875246815550715,"score_spread":0.1771575939298706,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}