{"id":"W62980418","doi":"","title":"Induction of IRF-3 and IRF-7 phosphorylation following activation of the RIG-I pathway.","year":2006,"lang":"en","type":"article","venue":"PubMed","topic":"interferon and immune responses","field":"Immunology and Microbiology","cited_by":94,"is_retracted":false,"has_abstract":true,"ca_institutions":"Terry Fox Research Institute","funders":"","keywords":"TRIF; Interferon regulatory factors; Signal transducing adaptor protein; Phosphorylation; RIG-I; Biology; Signal transduction; IRF3; Interferon; Cell biology; Innate immune system; NS3; Kinase; Molecular biology; Virology; Receptor; Toll-like receptor; Virus; Biochemistry; Hepatitis C virus","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002048403,0.00006072547,0.0001125262,0.00005447841,0.00006116367,0.000003385211,0.00005935701,0.0001036905,0.00001480717],"category_scores_gemma":[0.00008847022,0.00004396209,0.00006084554,0.00009385899,0.00008210957,0.00008376945,0.00002916212,0.000085923,0.00000189747],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00002063569,"about_ca_system_score_gemma":0.00001363777,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0003221976,"about_ca_topic_score_gemma":0.00001117875,"domain_scores_codex":[0.9994693,0.0001098146,0.0001923173,0.00008710901,0.00002592283,0.0001154753],"domain_scores_gemma":[0.9996522,0.00005942711,0.0001361271,0.0001157369,0.00003298462,0.0000034922],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.000234815,0.0000643069,0.01075949,0.00001314971,0.00005787923,6.966411e-8,0.0001794571,0.00000450814,0.9242619,0.00101333,0.0002928989,0.06311824],"study_design_scores_gemma":[0.0003037465,0.00001355053,0.410787,0.000008459048,0.000009687114,0.000002152725,0.00005320407,8.741516e-7,0.5870096,0.000133705,0.001650077,0.00002791323],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9970117,0.000673574,0.00004674274,0.0001110737,0.0004567748,0.0002441174,0.000003440787,0.00001140877,0.001441172],"genre_scores_gemma":[0.9980906,0.000007006779,0.000006744143,0.00001488038,0.00001177816,0.00005115062,0.0000111433,0.000005029468,0.001801626],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.4000275,"threshold_uncertainty_score":0.1792722,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.0103670876252009,"score_gpt":0.1875246815550715,"score_spread":0.1771575939298706,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}