{"id":"W631553572","doi":"10.1016/s1878-6480(15)30022-7","title":"0325 : Catabolism of leucine in the heart inhibits glucose transport","year":2015,"lang":"en","type":"article","venue":"Archives of Cardiovascular Diseases Supplements","topic":"Metabolism, Diabetes, and Cancer","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":false,"ca_institutions":"Université de Montréal; Montreal Heart Institute","funders":"","keywords":"Leucine; GLUT4; Glucose transporter; Glucose uptake; Internal medicine; Endocrinology; Insulin; Catabolism; PI3K/AKT/mTOR pathway; Phosphorylation; Snf3; Biochemistry; Amino acid; Metabolism; Medicine; Biology; Signal transduction","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003306521,0.0001755429,0.0004392045,0.00008140931,0.00002393902,0.00000499257,0.000357833,0.00003987224,0.00001495727],"category_scores_gemma":[0.00005326391,0.0001397625,0.0006552589,0.0001293637,0.0001598871,0.000008778094,0.00007756054,0.00006161816,0.000001371316],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000004371739,"about_ca_system_score_gemma":0.0001639416,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0002193165,"about_ca_topic_score_gemma":0.00004518893,"domain_scores_codex":[0.9983175,0.0002322654,0.0003648049,0.0003130961,0.0004929395,0.0002793845],"domain_scores_gemma":[0.998924,0.00001723746,0.0000731008,0.0007994091,0.00005681381,0.0001294804],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.002734902,0.003628428,0.4432602,0.001530844,0.00943217,0.00005081484,0.007280189,0.01046453,0.05520678,0.0009642841,0.01646407,0.4489828],"study_design_scores_gemma":[0.005098636,0.0002338482,0.1098848,0.0000650932,0.0006736447,0.000006147472,0.0005861641,0.00001177771,0.135576,0.0005090071,0.747048,0.0003068197],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.6677752,0.3307926,0.000209908,0.0000194036,0.00008586421,0.0003014358,0.0005056426,0.000003202653,0.000306736],"genre_scores_gemma":[0.9754372,0.02314939,0.0002213943,0.0001292794,0.0001701879,0.00006637609,0.0007927027,0.00001994877,0.00001358309],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.730584,"threshold_uncertainty_score":0.5699351,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01213178310932787,"score_gpt":0.2434616452124397,"score_spread":0.2313298621031119,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}