{"id":"W63425872","doi":"10.1016/j.jacc.2014.08.021","title":"A Polypill Strategy to Improve Adherence","year":2014,"lang":"en","type":"article","venue":"Journal of the American College of Cardiology","topic":"Medication Adherence and Compliance","field":"Medicine","cited_by":351,"is_retracted":false,"has_abstract":false,"ca_institutions":"University Health Network","funders":"","keywords":"Medicine; Polypill; Tolerability; Fixed-dose combination; Randomized controlled trial; Internal medicine; Clinical endpoint; Aspirin; Statin; Ramipril; Pill; Myocardial infarction; Simvastatin; Pharmacology; Blood pressure; Adverse effect","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001032906,0.0003856336,0.0004827305,0.000765219,0.0008926369,0.0007150577,0.0005074568,0.001722843,0.0079086],"category_scores_gemma":[0.003967213,0.0001261307,0.0006150667,0.0003743669,0.0001424446,0.0007994572,0.0006151836,0.001531411,0.0008858087],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0006921511,"about_ca_system_score_gemma":0.002250603,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.002706076,"about_ca_topic_score_gemma":0.008652865,"domain_scores_codex":[0.9990016,0.0003288316,0.0001010788,0.0001046871,0.0003598335,0.0001039768],"domain_scores_gemma":[0.9983587,0.0004348692,0.000219696,0.00006909942,0.0002562739,0.0006614584],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"observational","study_design_scores_codex":[0.001651818,0.02155122,0.01591043,0.0006823927,0.0002179046,0.0009076453,0.0003731722,0.0003784955,0.003319897,0.001606694,0.0336958,0.9197047],"study_design_scores_gemma":[0.01609487,0.05321469,0.6165488,0.005691218,0.003099395,0.007418024,0.002091704,0.01815165,0.01184959,0.01532384,0.250105,0.0004112048],"study_design_candidate":"observational","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.6697514,0.02138895,0.021954,0.1506252,0.006370312,0.003796178,0.0008187778,0.001657542,0.1236376],"genre_scores_gemma":[0.9003135,0.00568664,0.03512576,0.03961329,0.003789436,0.001002388,0.0003009491,0.00006003531,0.01410793],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0079086,"threshold_uncertainty_score":0.02645695,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02161874227797579,"score_gpt":0.3027819920315416,"score_spread":0.2811632497535658,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}