{"id":"W64619986","doi":"10.1016/j.cryobiol.2014.06.061","title":"P09","year":2014,"lang":"en","type":"article","venue":"Cryobiology","topic":"PI3K/AKT/mTOR signaling in cancer","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":false,"ca_institutions":"Carleton University","funders":"","keywords":"P70-S6 Kinase 1; EIF4E; eIF4A; mTORC1; Cell biology; PI3K/AKT/mTOR pathway; Eukaryotic translation; Translation (biology); Ribosomal protein s6; Protein biosynthesis; Messenger RNA; Initiation factor; Biology; Phosphorylation; Eukaryotic initiation factor; Biochemistry; Gene; Signal transduction","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":["insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.0003145336,0.0005037116,0.0002291496,0.0009035019,0.001138852,0.002295985,0.0007277088,0.00144425,0.6392279],"category_scores_gemma":[0.0007714704,0.0002020387,0.0003574527,0.0005763791,0.0005156324,0.000636631,0.00100336,0.001147953,0.3561414],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0009162544,"about_ca_system_score_gemma":0.0009306699,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.002117033,"about_ca_topic_score_gemma":0.004046653,"domain_scores_codex":[0.9998296,0.00001599506,0.000007002266,0.00003579064,0.00008469645,0.00002675525],"domain_scores_gemma":[0.9996418,0.00004547976,0.00001934479,0.00005368892,0.0001206846,0.0001189689],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"not_applicable","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0001641768,0.00006699985,0.0003784764,0.000169657,0.000008492702,0.0003236621,0.0000449699,0.00009955585,0.005544491,0.01670014,0.7683697,0.2081297],"study_design_scores_gemma":[0.00001494887,0.00002801837,0.0008295301,0.00005068998,0.000003002034,0.0003298801,0.00002191827,0.00007248246,0.001533212,0.002385951,0.9947265,0.000003890286],"study_design_candidate":"not_applicable","study_design_consensus":"not_applicable","genre_codex":"other","genre_gemma":"other","genre_scores_codex":[0.001840459,0.002106371,0.001674378,0.004983451,0.004382882,0.00009892328,0.001638644,0.0007155049,0.9825593],"genre_scores_gemma":[0.006778411,0.001063973,0.000852557,0.0009578999,0.0008988383,0.00004061984,0.0008370244,0.0001478007,0.988423],"genre_candidate":"other","genre_consensus":"other","teacher_disagreement_score":0.3607721,"threshold_uncertainty_score":0,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.005224149621181607,"score_gpt":0.2336695051901261,"score_spread":0.2284453555689445,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}