{"id":"W64856605","doi":"10.1161/circ.120.suppl_18.s1139-b","title":"Abstract 5681: GPR30 is Required for the Pro-apoptotic Effects of Estrogen in Vascular Smooth Muscle Cells","year":2009,"lang":"en","type":"article","venue":"Circulation","topic":"Estrogen and related hormone effects","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"Robarts Clinical Trials","funders":"","keywords":"Medicine; GPER; Estrogen; Vascular smooth muscle; Apoptosis; Estrogen receptor; Smooth muscle; Internal medicine; Endocrinology; Cell biology; Cancer research; Biochemistry; Breast cancer","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001637833,0.0004154239,0.0005039119,0.0001699844,0.0002844547,0.0003192076,0.0002750955,0.0004740474,0.009404151],"category_scores_gemma":[0.0002406741,0.0002162606,0.0003775974,0.0002015296,0.0002759868,0.0002655306,0.0003802849,0.0008812266,0.003914312],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003109942,"about_ca_system_score_gemma":0.0002421977,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0006189366,"about_ca_topic_score_gemma":0.0005324711,"domain_scores_codex":[0.9997172,0.00004201597,0.00003330599,0.00007056112,0.00007189698,0.0000651257],"domain_scores_gemma":[0.9997706,0.00003172484,0.00006176317,0.00003231916,0.00002459533,0.00007911587],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0004258394,0.00003460803,0.0001130916,0.00005094013,0.00000489317,0.0001398254,0.00001325382,0.00002811577,0.9977182,0.00008053365,0.0002109496,0.001179806],"study_design_scores_gemma":[0.0002866067,0.001303399,0.03838687,0.00003971389,0.00004334069,0.002877106,0.0001526103,0.001073248,0.9374142,0.0002224173,0.01817829,0.00002211752],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9836062,0.003424064,0.003248376,0.0007233478,0.0002316182,0.00006075363,0.003607441,0.0002542795,0.004843922],"genre_scores_gemma":[0.9733893,0.001869829,0.002523933,0.0003870728,0.000100422,0.0001366711,0.008099509,0.00008778504,0.01340557],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.009404151,"threshold_uncertainty_score":0.03146005,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.008032646101328159,"score_gpt":0.2379164022716581,"score_spread":0.22988375617033,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}