{"id":"W648994771","doi":"10.1371/journal.pone.0129561","title":"Negative Regulation of TGFβ Signaling by Stem Cell Antigen-1 Protects against Ischemic Acute Kidney Injury","year":2015,"lang":"en","type":"article","venue":"PLoS ONE","topic":"Renal and related cancers","field":"Biochemistry, Genetics and Molecular Biology","cited_by":17,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"University of Ottawa; National Institute of Diabetes and Digestive and Kidney Diseases; Texas Tech University; National Institutes of Health; Children's Hospital of Philadelphia; Massachusetts General Hospital","keywords":"Acute kidney injury; Kidney; Renal stem cell; Medicine; SMAD; Creatinine; Kidney disease; Internal medicine; Renal function; Endocrinology; Acute tubular necrosis; Stem cell; Pathology; Biology; Receptor; Cell biology","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001507306,0.0004457649,0.0005006457,0.0002549104,0.0001182205,0.000326849,0.0002470432,0.0002362317,0.00109886],"category_scores_gemma":[0.0001313686,0.0001198553,0.0002588098,0.0001336255,0.0002727438,0.0002217396,0.0001511841,0.001045985,0.0003130569],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001311431,"about_ca_system_score_gemma":0.0002757356,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0002366788,"about_ca_topic_score_gemma":0.000407748,"domain_scores_codex":[0.9998897,0.00001479808,0.00001492215,0.00002127443,0.00002632112,0.00003292001],"domain_scores_gemma":[0.9998714,0.00001205761,0.00004268485,0.00001413423,0.00001701958,0.00004273764],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0005979686,0.0002214971,0.0003511319,0.0001205261,0.00001956944,0.00004919766,0.00002438294,0.00008406673,0.9936678,0.0001185867,0.0001279323,0.00461745],"study_design_scores_gemma":[0.0001886626,0.002270133,0.009282098,0.00003224016,0.000102911,0.0002353187,0.00006721848,0.001319345,0.9826456,0.0001396482,0.003705715,0.00001094043],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9934579,0.003307159,0.001660203,0.0001915064,0.00009976484,0.00002909562,0.0002637224,0.0001477547,0.0008430746],"genre_scores_gemma":[0.9942936,0.002204319,0.001202367,0.00008949498,0.00003634143,0.00005321572,0.0005826755,0.00001993653,0.001517903],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.00109886,"threshold_uncertainty_score":0.003676116,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01597853890811632,"score_gpt":0.2096461030234346,"score_spread":0.1936675641153183,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}