{"id":"W6557504","doi":"10.1016/j.vaccine.2011.07.043","title":"Challenges in dendritic cells-based therapeutic vaccination in HIV-1 infection","year":2011,"lang":"en","type":"article","venue":"Vaccine","topic":"Immunotherapy and Immune Responses","field":"Immunology and Microbiology","cited_by":76,"is_retracted":false,"has_abstract":false,"ca_institutions":"McGill University Health Centre","funders":"","keywords":"Vaccination; Immunotherapy; Immunology; Clinical trial; Medicine; Immune system; Antigen; Immunization; Dendritic cell; Cancer immunotherapy; Immunogen; Ex vivo; In vivo; Biology; Antibody; Internal medicine","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.0003399826,0.0001553082,0.000221313,0.0004660741,0.0000518033,0.000004875511,0.0001186737,0.0002086472,0.001245447],"category_scores_gemma":[0.0000263951,0.0001445421,0.00005237548,0.0002298781,0.00000789303,0.0001247074,0.00001706426,0.0002541338,0.0003817588],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00007020612,"about_ca_system_score_gemma":0.00003549413,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000234515,"about_ca_topic_score_gemma":0.0006906426,"domain_scores_codex":[0.9988134,0.0003516195,0.0002984123,0.0002288184,0.0000205347,0.0002872246],"domain_scores_gemma":[0.9995554,0.00009791637,0.00006851982,0.0002412459,0.00002981794,0.000007083114],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","study_design_scores_codex":[0.003954396,0.001800124,0.09250245,0.000104515,0.000115355,0.00002639512,0.004237234,0.0000461603,0.6984121,0.001733673,0.000160264,0.1969073],"study_design_scores_gemma":[0.003715347,0.0002933717,0.7412913,0.00005464364,0.000009932031,0.00001539929,0.0001334523,0.00002324232,0.2501462,0.0002336306,0.003918595,0.0001649001],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.965278,0.03118901,0.000182137,0.0004382783,0.0006378862,0.0003226923,0.000002233523,0.00008041498,0.001869351],"genre_scores_gemma":[0.9970385,0.002338588,0.00002993368,0.0001149116,0.000009473046,0.00004884832,0.00001861818,0.00001884723,0.0003822499],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.6487888,"threshold_uncertainty_score":0.9996675,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.04229742211494376,"score_gpt":0.2581021038505168,"score_spread":0.215804681735573,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}