{"id":"W6887925802","doi":"10.17863/cam.64252","title":"Pathway and network analysis of more than 2500 whole cancer genomes.","year":2018,"lang":"en","type":"article","venue":"Apollo (University of Cambridge)","topic":"Cancer Genomics and Diagnostics","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":false,"ca_institutions":"","funders":"Natural Sciences and Engineering Research Council of Canada; National Cancer Institute; National Institutes of Health; Novo Nordisk Fonden; Fonds Wetenschappelijk Onderzoek; Novo Nordisk; Innovationsfonden; Government of Ontario; Canadian Institutes of Health Research; Cancer Research Society","keywords":"Frameshift mutation; Mutation; Gene; Proteogenomics; Genome","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0006096538,0.0007583791,0.0006797123,0.003175955,0.0007908971,0.000879091,0.0004508639,0.0003961326,0.005902286],"category_scores_gemma":[0.001274287,0.0002009501,0.001552942,0.004164961,0.0001953008,0.0005244653,0.0008363453,0.0007039248,0.001481708],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0007087178,"about_ca_system_score_gemma":0.001222854,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.007831461,"about_ca_topic_score_gemma":0.01600676,"domain_scores_codex":[0.9995334,0.0001007319,0.00002682082,0.0001756376,0.0001001075,0.00006337486],"domain_scores_gemma":[0.9994335,0.0002450958,0.00008148374,0.00007396995,0.00008922981,0.0000766765],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"observational","study_design_scores_codex":[0.003544383,0.0004561147,0.1782495,0.02002026,0.01002237,0.002083057,0.001132973,0.04920793,0.2653451,0.01908552,0.1658851,0.2849678],"study_design_scores_gemma":[0.0002605887,0.0005798697,0.4552507,0.001047026,0.004217962,0.001887643,0.000960124,0.06151114,0.03435375,0.02784532,0.4118772,0.0002086518],"study_design_candidate":"observational","study_design_consensus":null,"genre_codex":"dataset","genre_gemma":"empirical","genre_scores_codex":[0.260312,0.0164721,0.02553052,0.00134677,0.0002091982,0.0001888793,0.6792138,0.005469831,0.01125686],"genre_scores_gemma":[0.3418655,0.007373451,0.05179878,0.0004154607,0.00005028838,0.0003521715,0.5932229,0.000496589,0.004424832],"genre_candidate":"empirical","genre_consensus":null,"teacher_disagreement_score":0.007831461,"threshold_uncertainty_score":0.01974511,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.005991753629465776,"score_gpt":0.2079191241189485,"score_spread":0.2019273704894827,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}