{"id":"W6901592474","doi":"10.60692/8v12t-q4g46","title":"Human inherited CCR2 deficiency underlies progressive polycystic lung disease","year":2024,"lang":"en","type":"article","venue":"Greater South Information System","topic":"Immunodeficiency and Autoimmune Disorders","field":"Immunology and Microbiology","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"McGill University","funders":"","keywords":"CCR2; Chemokine; Chemokine receptor; Monocyte; Lung; Pulmonary alveolar proteinosis; CC chemokine receptors","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001289925,0.0006938891,0.0002813817,0.000291174,0.0003484647,0.0002123386,0.0001602757,0.0003184753,0.002235575],"category_scores_gemma":[0.0003662814,0.00009504014,0.000156301,0.0002138284,0.0003673888,0.0001273562,0.0002996232,0.0002969231,0.0003431297],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001422399,"about_ca_system_score_gemma":0.0001739422,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001042919,"about_ca_topic_score_gemma":0.001056981,"domain_scores_codex":[0.9998709,0.00002496215,0.00001377291,0.00004081231,0.00002678058,0.00002269105],"domain_scores_gemma":[0.9998463,0.00003400144,0.00004148851,0.00001356972,0.00001716989,0.00004739955],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","study_design_scores_codex":[0.001347184,0.0002124364,0.1147993,0.0004992938,0.0002809262,0.2342565,0.001184531,0.000851417,0.5804842,0.003324577,0.005270841,0.05748871],"study_design_scores_gemma":[0.0001539314,0.0008000688,0.2330554,0.0001026787,0.0003322735,0.6983628,0.000340666,0.001349936,0.0451439,0.0009624981,0.01933928,0.00005664295],"study_design_candidate":"observational","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9906549,0.002922461,0.002927404,0.0002397971,0.000049739,0.00002957062,0.0004857536,0.00009745318,0.002592869],"genre_scores_gemma":[0.9974336,0.000599406,0.0008578314,0.00007525009,0.00002816539,0.000007581227,0.0002590713,0.00001155423,0.0007275181],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002235575,"threshold_uncertainty_score":0.007478714,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01703032331197554,"score_gpt":0.2280901434671931,"score_spread":0.2110598201552175,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}