{"id":"W6901637295","doi":"10.60692/jvfqb-63t55","title":"Structural Interaction and Functional Regulation of Polycystin-2 by Filamin","year":2012,"lang":"en","type":"article","venue":"Greater South Information System","topic":"Genetic and Kidney Cyst Diseases","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Alberta","funders":"","keywords":"Filamin; FLNA; Cytoskeleton; Actin cytoskeleton; Actin; Ion channel; Gene isoform; Signal transduction; TRPC1","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001044583,0.0002088879,0.0001212352,0.0001080031,0.0001895326,0.0003414185,0.0002321931,0.0002780957,0.0005726017],"category_scores_gemma":[0.000174153,0.0001133188,0.0002065463,0.00009590111,0.000232045,0.0002160386,0.000222637,0.0003774137,0.0002687195],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004521641,"about_ca_system_score_gemma":0.0001152587,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0007047408,"about_ca_topic_score_gemma":0.0007191029,"domain_scores_codex":[0.9998548,0.00003033521,0.00001520305,0.00003041577,0.00003924295,0.00002991676],"domain_scores_gemma":[0.9998829,0.00002367598,0.00003858245,0.00001427721,0.00001729349,0.00002324716],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00003854035,0.000006731868,0.0001348341,0.000008322902,0.000001795638,0.00005463727,0.000006247533,0.00002437369,0.9994339,0.00005005131,0.00000826033,0.0002323755],"study_design_scores_gemma":[0.000009111097,0.00005183685,0.01159306,0.000003592612,0.00001082671,0.0005094509,0.00003894824,0.001206353,0.9856338,0.00005951224,0.0008786549,0.000004821887],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9979911,0.0005829649,0.0008832127,0.00006583847,0.000009639968,0.000003302127,0.00005407891,0.00001168949,0.0003981413],"genre_scores_gemma":[0.9984471,0.0002849306,0.0005914164,0.00002706168,0.000003139843,0.000005407223,0.0001179799,0.000007174838,0.0005158408],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0007047408,"threshold_uncertainty_score":0.003280699,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01523199758070532,"score_gpt":0.2002225122158388,"score_spread":0.1849905146351335,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}