{"id":"W6901712213","doi":"10.6084/m9.figshare.12010437.v1","title":"Additional file 1 of Assessing the effect of genetic markers on drug immunogenicity from a mechanistic model-based approach","year":2020,"lang":"en","type":"article","venue":"Figshare","topic":"vaccines and immunoinformatics approaches","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"Centre Hospitalier Universitaire Sainte-Justine","funders":"","keywords":"Immunogenicity; Drug; Genetic marker; Drug response; Identification (biology); Drug discovery","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.00002971009,0.000139706,0.0001678729,0.00001346866,0.00005407572,0.00001913081,0.0002785394,0.00007386271,0.3160592],"category_scores_gemma":[0.0009824404,0.00009959824,0.0001526974,0.00007170691,0.00001133482,0.000003862188,0.000102311,0.00009067716,0.00003280583],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00000621197,"about_ca_system_score_gemma":0.00008793885,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000002735813,"about_ca_topic_score_gemma":2.386346e-7,"domain_scores_codex":[0.9992977,0.00005952579,0.0002219592,0.0001637903,0.0001433638,0.0001136629],"domain_scores_gemma":[0.9991395,0.0003013749,0.0002053874,0.0002657191,0.00005254926,0.00003546034],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"not_applicable","study_design_gemma":"simulation_or_modeling","study_design_scores_codex":[0.0001000814,0.00002228569,0.000002986111,0.0001903227,0.00005734702,2.185438e-7,0.00002202376,0.007330646,0.004482577,5.763032e-7,0.9871991,0.0005918012],"study_design_scores_gemma":[0.00091169,0.0007204774,0.001321348,0.0008196851,0.00005997372,0.000002022651,0.0001022486,0.8687354,0.09650596,0.00001982196,0.03047461,0.0003267505],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"dataset","genre_gemma":"dataset","genre_scores_codex":[0.005527813,0.00009222586,0.0002852111,0.00001821854,0.000005391546,0.0002192595,0.9928651,0.000006197041,0.0009805791],"genre_scores_gemma":[0.3401869,4.88622e-7,0.002276472,0.000110741,0.00003822492,0.0002287459,0.6571278,0.00001371041,0.00001689259],"genre_candidate":"dataset","genre_consensus":"dataset","teacher_disagreement_score":0.9567245,"threshold_uncertainty_score":0.6845661,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01584230913678853,"score_gpt":0.2185216499607605,"score_spread":0.202679340823972,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}