{"id":"W6901869847","doi":"10.6084/m9.figshare.13627439","title":"Additional file 1 of Efficacy and safety of CD22 chimeric antigen receptor (CAR) T cell therapy in patients with B cell malignancies: a protocol for a systematic review and meta-analysis","year":2021,"lang":"en","type":"article","venue":"Open MIND","topic":"CAR-T cell therapy research","field":"Medicine","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"BC Cancer Agency; University of Ottawa; Western University; Ottawa Hospital; University of British Columbia","funders":"","keywords":"Chimeric antigen receptor; CD22; B cell; Immunotherapy; CAR T-cell therapy; T cell; Antigen","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":["insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.006732112,0.002348115,0.006058443,0.005342019,0.0007958455,0.001942879,0.001621693,0.001840947,0.5605311],"category_scores_gemma":[0.04251416,0.001289185,0.007052026,0.006923075,0.0005192544,0.00299991,0.001388299,0.001392546,0.01450528],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.003088105,"about_ca_system_score_gemma":0.005081951,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.004762033,"about_ca_topic_score_gemma":0.01373468,"domain_scores_codex":[0.9971364,0.0008456102,0.001176364,0.0003393234,0.0003396052,0.000162798],"domain_scores_gemma":[0.9714475,0.02082187,0.004681739,0.000614978,0.002144019,0.0002897469],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"systematic_review","study_design_gemma":"not_applicable","study_design_scores_codex":[0.003490655,0.00009020249,0.0006521728,0.8986405,0.003115979,0.0000823119,0.0001334133,0.0004398113,0.0003940176,0.001045186,0.07827857,0.01363715],"study_design_scores_gemma":[0.1000032,0.002548372,0.02262997,0.4604685,0.0485018,0.0006639582,0.0005585157,0.002506745,0.001711007,0.01069172,0.3492146,0.0005016024],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"dataset","genre_gemma":"protocol","genre_scores_codex":[0.002000686,0.00961447,0.002205151,0.001091263,0.0002805818,0.05220676,0.9281968,0.0004864414,0.003917823],"genre_scores_gemma":[0.03237751,0.01752428,0.02985706,0.003893121,0.0006088022,0.6707903,0.2176587,0.0005625573,0.02672765],"genre_candidate":"protocol","genre_consensus":null,"teacher_disagreement_score":0.5605311,"threshold_uncertainty_score":0.6268489,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.05910366029784501,"score_gpt":0.3460429781788807,"score_spread":0.2869393178810357,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}