{"id":"W6901932104","doi":"10.60692/p3r6g-9v481","title":"MIBiG 3.0: a community-driven effort to annotate experimentally validated biosynthetic gene clusters","year":2022,"lang":"en","type":"article","venue":"Greater South Information System","topic":"Microbial Natural Products and Biosynthesis","field":"Medicine","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Ottawa; Simon Fraser University; University of Manitoba","funders":"Biotechnology and Biological Sciences Research Council","keywords":"ENCODE; Annotation; Domain (mathematical analysis); Gene cluster; Product (mathematics); Gene; Gene nomenclature; Gene Annotation; Cluster (spacecraft); Protein domain","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.01158161,0.002572604,0.00280067,0.0153393,0.002199934,0.005353746,0.005424149,0.002375269,0.01395069],"category_scores_gemma":[0.02818029,0.001781651,0.002267633,0.01183839,0.001187138,0.004177302,0.01111474,0.003123007,0.01633221],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.002148859,"about_ca_system_score_gemma":0.006124319,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.005512384,"about_ca_topic_score_gemma":0.007801344,"domain_scores_codex":[0.9944653,0.001077499,0.0009231751,0.001453539,0.001717634,0.0003628765],"domain_scores_gemma":[0.9854347,0.003991881,0.001782161,0.004193728,0.003028733,0.001568854],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"not_applicable","study_design_gemma":"not_applicable","study_design_scores_codex":[0.006743698,0.0008835891,0.02991341,0.01452653,0.001324811,0.001449723,0.003645941,0.007839982,0.1501235,0.02049719,0.6052772,0.1577744],"study_design_scores_gemma":[0.00060745,0.0006261909,0.02744533,0.001230465,0.0005196488,0.001103549,0.0008002057,0.01271019,0.04268761,0.009849403,0.9019705,0.0004495876],"study_design_candidate":"not_applicable","study_design_consensus":"not_applicable","genre_codex":"dataset","genre_gemma":"software","genre_scores_codex":[0.04651736,0.002613273,0.04893095,0.001026827,0.0004672168,0.0009724031,0.828101,0.0601007,0.01127037],"genre_scores_gemma":[0.01256822,0.0004387322,0.05698432,0.0002716357,0.00002739285,0.0007878307,0.9244931,0.003289414,0.00113926],"genre_candidate":"software","genre_consensus":null,"teacher_disagreement_score":0.0153393,"threshold_uncertainty_score":0.06125015,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03550325507258808,"score_gpt":0.2335396536366602,"score_spread":0.1980363985640721,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}