{"id":"W6902073298","doi":"10.6084/m9.figshare.26378014","title":"Additional file 1 of Pembrolizumab plus epacadostat in patients with recurrent/metastatic head and neck squamous cell carcinoma (KEYNOTE-669/ECHO-304): a phase 3, randomized, open-label study","year":2024,"lang":"en","type":"article","venue":"Open MIND","topic":"Head and Neck Cancer Studies","field":"Medicine","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"Jewish General Hospital; Hôtel-Dieu de Québec","funders":"","keywords":"Pembrolizumab; Head and neck squamous-cell carcinoma; Table (database); Head and neck; Basal cell; Head and neck cancer; Phases of clinical research","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":["insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.002847989,0.001167343,0.001548545,0.0006371341,0.0009253875,0.001106591,0.001131185,0.001173611,0.7979242],"category_scores_gemma":[0.01808178,0.0006107771,0.001081952,0.001299595,0.0002486648,0.001292677,0.000441772,0.001271597,0.04992219],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.001143822,"about_ca_system_score_gemma":0.002338921,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.002077234,"about_ca_topic_score_gemma":0.005228202,"domain_scores_codex":[0.9991094,0.0003380723,0.0001599681,0.0001397388,0.0001372154,0.0001155483],"domain_scores_gemma":[0.9886352,0.00723711,0.001668777,0.0006949733,0.001289376,0.0004746177],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"not_applicable","study_design_gemma":"randomized_trial","study_design_scores_codex":[0.0462022,0.001749801,0.001333552,0.01799973,0.0005462468,0.0001013607,0.0001115742,0.0007539454,0.0003750653,0.002321577,0.8882251,0.04027983],"study_design_scores_gemma":[0.5275683,0.01061547,0.02102264,0.00868228,0.001605149,0.000507088,0.0001897501,0.002783725,0.001632796,0.01053813,0.4146924,0.0001622208],"study_design_candidate":"randomized_trial","study_design_consensus":null,"genre_codex":"dataset","genre_gemma":"other","genre_scores_codex":[0.002786529,0.0003621005,0.001047745,0.001059171,0.0002739747,0.01817949,0.9663315,0.0004978759,0.009461589],"genre_scores_gemma":[0.08944732,0.001694904,0.02049903,0.006608836,0.001075104,0.3319505,0.4605476,0.0007943237,0.08738241],"genre_candidate":"other","genre_consensus":null,"teacher_disagreement_score":0.7979242,"threshold_uncertainty_score":0.2882366,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.04180700019803163,"score_gpt":0.3457461596329453,"score_spread":0.3039391594349137,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}