{"id":"W6902168106","doi":"10.6084/m9.figshare.26378046","title":"Additional file 1 of Epacadostat plus pembrolizumab versus placebo plus pembrolizumab as first-line treatment for metastatic non-small cell lung cancer with high levels of programmed death-ligand 1: a randomized, double-blind phase 2 study","year":2024,"lang":"en","type":"article","venue":"Open MIND","topic":"Cancer Immunotherapy and Biomarkers","field":"Medicine","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Alberta","funders":"","keywords":"Pembrolizumab; Placebo; Lung cancer; Immunotherapy; Phases of clinical research; PD-L1","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":["insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.002166284,0.001390306,0.002111017,0.0008321742,0.000883024,0.00117204,0.001532403,0.001393299,0.8359858],"category_scores_gemma":[0.01791422,0.0007498847,0.001520034,0.001486652,0.0002594559,0.00134599,0.0005256998,0.001278926,0.06523159],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.001156123,"about_ca_system_score_gemma":0.002037241,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.002650706,"about_ca_topic_score_gemma":0.005623809,"domain_scores_codex":[0.99911,0.0003126236,0.0001447678,0.0001656616,0.0001385051,0.000128459],"domain_scores_gemma":[0.9872793,0.008919221,0.001554572,0.0006262784,0.001112286,0.0005083175],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"not_applicable","study_design_gemma":"randomized_trial","study_design_scores_codex":[0.052146,0.002131427,0.001894387,0.0212827,0.0008580583,0.0001306177,0.00008379788,0.001426463,0.0004179446,0.001848423,0.8652227,0.05255759],"study_design_scores_gemma":[0.4825923,0.01318811,0.02744118,0.008384172,0.002644221,0.0006907363,0.0001722325,0.003871359,0.001702419,0.01366088,0.4454295,0.0002228617],"study_design_candidate":"randomized_trial","study_design_consensus":null,"genre_codex":"dataset","genre_gemma":"empirical","genre_scores_codex":[0.001475086,0.0002859925,0.0005511233,0.0003729534,0.0001097205,0.003050504,0.9901848,0.0003331147,0.003636625],"genre_scores_gemma":[0.08025981,0.001815668,0.01601302,0.003706956,0.0007975427,0.08790819,0.7471391,0.00103387,0.06132595],"genre_candidate":"empirical","genre_consensus":null,"teacher_disagreement_score":0.8359858,"threshold_uncertainty_score":0.2339463,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.0844648644612435,"score_gpt":0.3801801566212285,"score_spread":0.295715292159985,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}